Weldon, William C, Oberste, M Steven, Pallansch, Mark A, Weldon, William C., Oberste, M. Steven, Pallansch, Mark A., William C. Weldon, M. Steven Oberste, Mark A. Pallansch
Abstract
Testing for neutralizing antibodies against polioviruses has been an established gold standard for assessing individual protection from disease, population immunity, vaccine efficacy studies, and other vaccine clinical trials. Detecting poliovirus specific IgM and IgA in sera and mucosal specimens has been proposed for evaluating the status of population mucosal immunity. More recently, there has been a renewed interest in using dried blood spot cards as a medium for sample collection to enhance surveillance of poliovirus immunity. Here, we describe the modified poliovirus microneutralization assay, poliovirus capture IgM and IgA ELISA assays, and dried blood spot polio serology procedures for the detection of antibodies against poliovirus serotypes 1, 2, and 3.
Pharmacology, Toxicology and Pharmaceutical Science
2
6%
Other
4
13%
Unknown
11
34%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2018.
All research outputs
#7,478,822
of 22,862,742 outputs
Outputs from Methods in molecular biology
#2,325
of 13,127 outputs
Outputs of similar age
#123,022
of 393,653 outputs
Outputs of similar age from Methods in molecular biology
#268
of 1,470 outputs
Altmetric has tracked 22,862,742 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,127 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,653 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 1,470 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.
