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Statistical Genomics

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Cover of 'Statistical Genomics'

Table of Contents

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    Book Overview
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    Chapter 1 Overview of Sequence Data Formats
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    Chapter 2 Integrative Exploratory Analysis of Two or More Genomic Datasets
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    Chapter 3 Study Design for Sequencing Studies
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    Chapter 4 Genomic Annotation Resources in R/Bioconductor
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    Chapter 5 The Gene Expression Omnibus Database
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    Chapter 6 A Practical Guide to The Cancer Genome Atlas (TCGA)
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    Chapter 7 Working with Oligonucleotide Arrays
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    Chapter 8 Meta-Analysis in Gene Expression Studies
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    Chapter 9 Practical Analysis of Genome Contact Interaction Experiments
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    Chapter 10 Quantitative Comparison of Large-Scale DNA Enrichment Sequencing Data
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    Chapter 11 Variant Calling From Next Generation Sequence Data
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    Chapter 12 Genome-Scale Analysis of Cell-Specific Regulatory Codes Using Nuclear Enzymes
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    Chapter 13 NGS-QC Generator: A Quality Control System for ChIP-Seq and Related Deep Sequencing-Generated Datasets
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    Chapter 14 Operating on Genomic Ranges Using BEDOPS
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    Chapter 15 GMAP and GSNAP for Genomic Sequence Alignment: Enhancements to Speed, Accuracy, and Functionality
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    Chapter 16 Visualizing Genomic Data Using Gviz and Bioconductor
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    Chapter 17 Introducing Machine Learning Concepts with WEKA
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    Chapter 18 Experimental Design and Power Calculation for RNA-seq Experiments
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    Chapter 19 It’s DE-licious: A Recipe for Differential Expression Analyses of RNA-seq Experiments Using Quasi-Likelihood Methods in edgeR
Attention for Chapter 1: Overview of Sequence Data Formats
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Chapter title
Overview of Sequence Data Formats
Chapter number 1
Book title
Statistical Genomics
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3578-9_1
Pubmed ID
Book ISBNs
978-1-4939-3576-5, 978-1-4939-3578-9
Authors

Hongen Zhang, Zhang, Hongen

Editors

Ewy Mathé, Sean Davis

Abstract

Next-generation sequencing experiment can generate billions of short reads for each sample and processing of the raw reads will add more information. Various file formats have been introduced/developed in order to store and manipulate this information. This chapter presents an overview of the file formats including FASTQ, FASTA, SAM/BAM, GFF/GTF, BED, and VCF that are commonly used in analysis of next-generation sequencing data.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 2%
Unknown 65 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 17%
Student > Bachelor 8 12%
Student > Doctoral Student 8 12%
Student > Ph. D. Student 6 9%
Researcher 3 5%
Other 8 12%
Unknown 22 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 23%
Computer Science 10 15%
Agricultural and Biological Sciences 9 14%
Engineering 3 5%
Unspecified 2 3%
Other 6 9%
Unknown 21 32%