Chapter title |
Use of DART-TOF-MS for Screening Drugs of Abuse
|
---|---|
Chapter number | 5 |
Book title |
Analysis of Drugs of Abuse
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-8579-1_5 |
Pubmed ID | |
Book ISBNs |
978-1-4939-8578-4, 978-1-4939-8579-1
|
Authors |
Robert R. Steiner, Steiner, Robert R. |
Abstract |
Screening is an integral component of an analytical scheme to identify the presence of controlled substances in submissions to the crime laboratory. Many techniques are utilized, including color tests, thin-layer chromatography, and ultraviolet spectroscopy. While these are useful techniques to guide the examiner, all will, at best, categorize the material into a broad group of compounds. Direct Analysis in Real Time (DART), coupled with a time-of-flight (TOF) mass spectrometer, is an emerging technique that yields highly definitive screening data leading to the identity of controlled substances present in a case sample. Sample preparation is quick and simple and run times are typically only a few minutes. Collected data will allow the examiner to determine appropriate standards for confirmation, making the overall analysis much more efficient. Presented here is a guide to using this technique for the screening of case submissions for controlled substances. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 3 | 33% |
Student > Master | 2 | 22% |
Student > Ph. D. Student | 1 | 11% |
Professor > Associate Professor | 1 | 11% |
Unspecified | 1 | 11% |
Other | 0 | 0% |
Unknown | 1 | 11% |
Readers by discipline | Count | As % |
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Unspecified | 1 | 11% |
Psychology | 1 | 11% |
Biochemistry, Genetics and Molecular Biology | 1 | 11% |
Neuroscience | 1 | 11% |
Other | 1 | 11% |
Unknown | 1 | 11% |