↓ Skip to main content
What is this page? Embed badge

Obesity, Fatty Liver and Liver Cancer

Overview of attention for book
Cover of 'Obesity, Fatty Liver and Liver Cancer'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Introduction
  3. Altmetric Badge
    Chapter 2 Epidemiology and Etiologic Associations of Non-alcoholic Fatty Liver Disease and Associated HCC
  4. Altmetric Badge
    Chapter 3 Pathogenesis of NASH: How Metabolic Complications of Overnutrition Favour Lipotoxicity and Pro-Inflammatory Fatty Liver Disease
  5. Altmetric Badge
    Chapter 4 Chemokines and Chemokine Receptors in the Development of NAFLD
  6. Altmetric Badge
    Chapter 5 NAFLD Related-HCC: The Relationship with Metabolic Disorders
  7. Altmetric Badge
    Chapter 6 Hepatocellular Carcinoma in Obesity: Finding a Needle in the Haystack?
  8. Altmetric Badge
    Chapter 7 Dysregulated Epigenetic Modifications in the Pathogenesis of NAFLD-HCC
  9. Altmetric Badge
    Chapter 8 The Influence of Gut Microbial Metabolism on the Development and Progression of Non-alcoholic Fatty Liver Disease
  10. Altmetric Badge
    Chapter 9 Microbiota, Obesity and NAFLD
  11. Altmetric Badge
    Chapter 10 Autophagy, NAFLD and NAFLD-Related HCC
  12. Altmetric Badge
    Chapter 11 Animal Models of Non-alcoholic Fatty Liver Diseases and Its Associated Liver Cancer
  13. Altmetric Badge
    Chapter 12 Current Prevention and Treatment Options for NAFLD
Attention for Chapter 10: Autophagy, NAFLD and NAFLD-Related HCC
Altmetric Badge

Mentioned by

twitter
1 X user

Readers on

mendeley
40 Mendeley
Summary X
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Autophagy, NAFLD and NAFLD-Related HCC
Chapter number 10
Book title
Obesity, Fatty Liver and Liver Cancer
Published in
Advances in experimental medicine and biology, January 2018
DOI 10.1007/978-981-10-8684-7_10
Pubmed ID
29956211
Book ISBNs
978-9-81-108683-0, 978-9-81-108684-7
Authors

William K. K. Wu, Lin Zhang, Matthew T. V. Chan, Wu, William K. K., Zhang, Lin, Chan, Matthew T. V.

Abstract

Non-alcoholic fatty liver disease (NAFLD) will become a dominant cause of hepatocellular carcinoma (HCC) in the coming decade. Whereas the exact molecular mechanisms underlying the progression from simple steatosis, through steatohepatitis, to HCC remains largely unclear, emerging evidence has supported a central role of defective autophagy in the pathogenesis of NAFLD and its complications. Autophagy not only regulates lipid metabolism and insulin resistance, but also protects hepatocytes from injury and cell death. Nevertheless, in inflammation and tumorigenesis, the role of autophagy is more paradoxical. In NAFLD, defective hepatic autophagy occurs at multiple levels through numerous mechanisms and is causally linked to NAFLD-related HCC. In this chapter, we summarize the regulation and function of autophagy in NAFLD and highlight recent identification of potential pharmacological agents for restoring autophagic flux in NAFLD.

View on publisher site
X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 15%
Student > Ph. D. Student 6 15%
Researcher 4 10%
Other 2 5%
Student > Bachelor 2 5%
Other 2 5%
Unknown 18 45%
Readers by discipline Count As %
Medicine and Dentistry 8 20%
Biochemistry, Genetics and Molecular Biology 6 15%
Mathematics 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Social Sciences 1 3%
Other 3 8%
Unknown 20 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2018.
All research outputs
#20,525,274
of 23,094,276 outputs
Outputs from Advances in experimental medicine and biology
#4,002
of 4,976 outputs
Outputs of similar age
#378,496
of 442,658 outputs
Outputs of similar age from Advances in experimental medicine and biology
#197
of 237 outputs
Altmetric has tracked 23,094,276 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,976 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,658 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 237 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

This page is provided by Altmetric.