Report for: Immunotoxicity Testing

You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.

Chapter title	CD4 + T Cell Differentiation and Activation
Chapter number	20
Book title	Immunotoxicity Testing
Published in	Methods in molecular biology, January 2018
DOI	10.1007/978-1-4939-8549-4_20
Pubmed ID	29882148
Book ISBNs	978-1-4939-8548-7, 978-1-4939-8549-4
Authors	Jim Reed, Scott A. Wetzel, Reed, Jim, Wetzel, Scott A.
Abstract	The activation and differentiation of CD4+ T cells play a critical role in establishing and subsequently controlling protective adaptive immune responses. Flow cytometry is a powerful technique with which to assess the potential of xenobiotics to influence CD4+ T cell activation and differentiation. With flow cytometry, cells are stained with fluorochrome-conjugated antibodies and/or specific fluorescent probes to assess T cell activation, proliferation, effector cytokine production, and transcription factor expression. This technique allows for complex phenotypic analysis of tens to hundreds of thousands of individual cells very rapidly to assess the potential impact of a xenobiotic on CD4 effector differentiation and activation state.

View on publisher site Alert me about new mentions

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.

Geographical breakdown

Country	Count	As %
Unknown	1	100%

Demographic breakdown

Type	Count	As %
Members of the public	1	100%

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Unknown	19	100%

Demographic breakdown

Readers by professional status	Count	As %
Student > Bachelor	3	16%
Researcher	2	11%
Lecturer	2	11%
Student > Ph. D. Student	2	11%
Student > Doctoral Student	1	5%
Other	5	26%
Unknown	4	21%

Readers by discipline	Count	As %
Biochemistry, Genetics and Molecular Biology	7	37%
Immunology and Microbiology	2	11%
Medicine and Dentistry	2	11%
Pharmacology, Toxicology and Pharmaceutical Science	1	5%
Social Sciences	1	5%
Other	3	16%
Unknown	3	16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2018.

All research outputs

#18,639,173

of 23,090,520 outputs

Outputs from Methods in molecular biology

#7,987

of 13,206 outputs

Outputs of similar age

#330,849

of 442,634 outputs

Outputs of similar age from Methods in molecular biology

#950

of 1,499 outputs

Altmetric has tracked 23,090,520 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.

So far Altmetric has tracked 13,206 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.

Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,634 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.

We're also able to compare this research output to 1,499 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.

Immunotoxicity Testing

Table of Contents

Mentioned by

Citations

Readers on

X Demographics

Geographical breakdown

Demographic breakdown

Mendeley readers

Geographical breakdown

Demographic breakdown

Attention Score in Context