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Mendeley readers
| Chapter title |
Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective
|
|---|---|
| Chapter number | 61 |
| Book title |
Voltage-gated Sodium Channels: Structure, Function and Channelopathies
|
| Published in |
Handbook of experimental pharmacology, January 2017
|
| DOI | 10.1007/164_2017_61 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-990283-8, 978-3-31-990284-5
|
| Authors |
Tamer M. Gamal El-Din, Michael J. Lenaeus, William A. Catterall, Gamal El-Din, Tamer M., Lenaeus, Michael J., Catterall, William A. |
| Abstract |
Voltage-gated sodium channels initiate and propagate action potentials in excitable cells. They respond to membrane depolarization through opening, followed by fast inactivation that terminates the sodium current. This ON-OFF behavior of voltage-gated sodium channels underlays the coding of information and its transmission from one location in the nervous system to another. In this review, we explore and compare structural and functional data from prokaryotic and eukaryotic channels to infer the effects of evolution on sodium channel structure and function. |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 24% |
| Researcher | 3 | 18% |
| Student > Ph. D. Student | 3 | 18% |
| Lecturer > Senior Lecturer | 2 | 12% |
| Other | 1 | 6% |
| Other | 2 | 12% |
| Unknown | 2 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 7 | 41% |
| Neuroscience | 4 | 24% |
| Medicine and Dentistry | 2 | 12% |
| Physics and Astronomy | 1 | 6% |
| Agricultural and Biological Sciences | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 1 | 6% |