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Coordinating Organismal Physiology Through the Unfolded Protein Response

Overview of attention for book
Attention for Chapter 1: The Unfolded Protein Response in the Immune Cell Development: Putting the Caretaker in the Driving Seat
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Chapter title
The Unfolded Protein Response in the Immune Cell Development: Putting the Caretaker in the Driving Seat
Chapter number 1
Book title
Coordinating Organismal Physiology Through the Unfolded Protein Response
Published in
Current topics in microbiology and immunology, January 2017
DOI 10.1007/82_2017_1
Pubmed ID
Book ISBNs
978-3-31-978529-5, 978-3-31-978530-1
Authors

Simon J. Tavernier, Bart N. Lambrecht, Sophie Janssens, Tavernier, Simon J., Lambrecht, Bart N., Janssens, Sophie

Abstract

The endoplasmic reticulum (ER) is the primary site for the folding of proteins destined for the membranous compartment and the extracellular space. This elaborate function is coordinated by the unfolded protein response (UPR), a stress-activated cellular program that governs proteostasis. In multicellular organisms, cells have adopted specialized functions, which required functional adaptations of the ER and its UPR. Recently, it has become clear that in immune cells, the UPR has acquired functions that stretch far beyond its original scope. In this review, we will discuss the role of the UPR in the immune system and highlight the plasticity of this signaling cascade throughout immune cell development .

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 39%
Student > Ph. D. Student 3 17%
Researcher 3 17%
Student > Doctoral Student 1 6%
Other 1 6%
Other 1 6%
Unknown 2 11%
Readers by discipline Count As %
Immunology and Microbiology 4 22%
Pharmacology, Toxicology and Pharmaceutical Science 3 17%
Agricultural and Biological Sciences 3 17%
Biochemistry, Genetics and Molecular Biology 3 17%
Medicine and Dentistry 2 11%
Other 1 6%
Unknown 2 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2018.
All research outputs
#15,512,170
of 23,053,169 outputs
Outputs from Current topics in microbiology and immunology
#447
of 681 outputs
Outputs of similar age
#257,573
of 421,456 outputs
Outputs of similar age from Current topics in microbiology and immunology
#27
of 44 outputs
Altmetric has tracked 23,053,169 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 681 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,456 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.