| Chapter title |
The Diagnostics of Human Steroid Hormone Disorders
|
|---|---|
| Chapter number | 80 |
| Book title |
Current Concepts in Medical Research and Practice
|
| Published in |
Advances in experimental medicine and biology, January 2017
|
| DOI | 10.1007/5584_2017_80 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-974149-9, 978-3-31-974150-5
|
| Authors |
Małgorzata Dobosz, Aneta Manda-Handzlik, Beata Pyrżak, Urszula Demkow, Dobosz, Małgorzata, Manda-Handzlik, Aneta, Pyrżak, Beata, Demkow, Urszula |
| Abstract |
Disturbances of the steroidogenesis or altered peripheral metabolism of steroids may result in severe clinical manifestations. Therefore, prompt diagnosis and initiation of medical treatment are desirable. The diagnostics of disorders of steroid hormone production, metabolism, and action have been previously based on immunoassay tests. However, in a modern medical laboratory, due to low accuracy of immunoassays, this technique is continuously replaced by chromatographic separation methods coupled to mass spectrometric detection systems. In this review we present current advances in the diagnostics of adrenal gland disorders, focusing on the role of mass spectrometry in prenatal and newborn screening, and in the diagnostics of sexual maturation disorders. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 3 | 18% |
| Unspecified | 1 | 6% |
| Lecturer | 1 | 6% |
| Student > Doctoral Student | 1 | 6% |
| Student > Bachelor | 1 | 6% |
| Other | 5 | 29% |
| Unknown | 5 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 47% |
| Mathematics | 1 | 6% |
| Unspecified | 1 | 6% |
| Nursing and Health Professions | 1 | 6% |
| Biochemistry, Genetics and Molecular Biology | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 5 | 29% |