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The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy

Overview of attention for book
Cover of 'The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Introduction
  3. Altmetric Badge
    Chapter 2 The Neuropathological Grading of Huntington's Disease (HD).
  4. Altmetric Badge
    Chapter 3 The Cerebral Cortex in Huntington’s Disease (HD)
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    Chapter 4 Degeneration of Select Motor and Limbic Nuclei of the Thalamus in Huntington's Disease (HD).
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    Chapter 5 Consistent and Widespread Degeneration of the Cerebellum in Huntington’s Disease (HD)
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    Chapter 6 Elucidation of the Role of the Premotor Oculomotor Brainstem Nuclei in the Pathogenesis of Oculomotor Dysfunctions in Huntington’s Disease (HD)
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    Chapter 7 Widespread Brainstem Neurodegeneration in Huntington's Disease (HD).
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    Chapter 8 Intraneuronal Transport and Defense Mechanisms with Possible Pathogenetic Relevance in Huntington's Disease (HD).
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    Chapter 9 The Disease Protein Huntingtin and Neuronal Protein Aggregations in Huntington’s Disease (HD)
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    Chapter 10 Pathological Nerve Cell Alterations in Huntington's Disease (HD) and Their Possible Role for the Demise of Nerve Cells.
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    Chapter 11 Conclusions and Outlook
Attention for Chapter 4: Degeneration of Select Motor and Limbic Nuclei of the Thalamus in Huntington's Disease (HD).
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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Chapter title
Degeneration of Select Motor and Limbic Nuclei of the Thalamus in Huntington's Disease (HD).
Chapter number 4
Book title
The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy
Published in
Advances in anatomy embryology and cell biology, January 2015
DOI 10.1007/978-3-319-19285-7_4
Pubmed ID
26420154
Book ISBNs
978-3-31-919284-0, 978-3-31-919285-7
Authors

Rüb, Udo, Vonsattel, Jean Paul G, Heinsen, Helmut, Korf, Horst-Werner, Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf

Abstract

Although early neuropathological studies reported degenerative features in subcortical brain regions of HD patients (e.g., pallidum, subthalamic nucleus, substantia nigra, claustrum, amygdala) including the thalamus (e.g., global atrophy and volume loss of the thalamus; thalamic astrogliosis; reduced density of microneurons in its cerebellar territory, the ventrolateral nucleus; astrogliosis in the centromedian and parafascicular nuclei; shrinkage of the centromedian nucleus and its nerve cells) (see Chap. 1 ) (Borrell-Pagès et al. 2006; Dom et al. 1976; Finkbeiner and Mitra 2008; Lange and Aulich 1986; Lange et al. 1976; McCaughey 1961; McLardy 1948; Pfeiffer 1913; Terplan 1924; Vonsattel 2008; Vonsattel and DiFiglia 1998; Vonsattel et al. 1985; Walker 2007a, b), the involvement of the thalamus and the extent of its degeneration in HD have been neglected in more recent investigations. Therefore, the affection of the thalamic nuclei is currently not among the established degenerative features of HD.

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Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 1 100%
Readers by discipline Count As %
Neuroscience 1 100%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2015.
All research outputs
#13,448,755
of 22,829,683 outputs
Outputs from Advances in anatomy embryology and cell biology
#24
of 86 outputs
Outputs of similar age
#173,069
of 353,131 outputs
Outputs of similar age from Advances in anatomy embryology and cell biology
#4
of 12 outputs
Altmetric has tracked 22,829,683 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 86 research outputs from this source. They receive a mean Attention Score of 2.2. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,131 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.

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