Chapter title |
Anti-neutrophil cytoplasm antibodies in HIV infection.
|
---|---|
Chapter number | 58 |
Book title |
ANCA-Associated Vasculitides
|
Published in |
Advances in experimental medicine and biology, January 1993
|
DOI | 10.1007/978-1-4757-9182-2_58 |
Pubmed ID | |
Book ISBNs |
978-1-4757-9184-6, 978-1-4757-9182-2
|
Authors |
Savige, J A, Chang, L, Crowe, S M, J. A. Savige, L. Chang, S. M. Crowe, Savige, J. A., Chang, L., Crowe, S. M. |
Abstract |
Sera from 105 HIV-infected patients were tested for anti-neutrophil cytoplasm antibodies (ANCA) by indirect immunofluorescence (IIF), by specific ELISAs using target proteins of ANCA and by a neutrophil cytoplasm extract ELISA. Forty-four sera were positive. These included 18 positive by IIF, 7 with anti-neutrophil proteinase 3 antibodies, 26 with anti-myeloperoxidase antibodies and 2 with anti-elastase antibodies. Four sera were positive in the neutrophil cytoplasm extract ELISA but not in the specific ELISAs. None of these patients had clinical evidence of a cutaneous or systemic vasculitis. In addition there was no correlation between the presence of ANCA and the stage of disease, intercurrent bacterial or viral infection, anti-nuclear antibodies (ANA) and positive hepatitis B or syphilis serology. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 8 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 2 | 25% |
Professor | 2 | 25% |
Student > Bachelor | 1 | 13% |
Lecturer | 1 | 13% |
Student > Master | 1 | 13% |
Other | 1 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 75% |
Psychology | 1 | 13% |
Environmental Science | 1 | 13% |