Chapter title |
Acute megakaryoblastic leukemia: a case report.
|
---|---|
Chapter number | 69 |
Book title |
Acute Leukemias II
|
Published in |
Haematology and blood transfusion, January 1990
|
DOI | 10.1007/978-3-642-74643-7_69 |
Pubmed ID | |
Book ISBNs |
978-3-54-050984-4, 978-3-64-274643-7
|
Authors |
Donhuijsen-Ant, R, Schadeck-Gressel, C, Schmidt, U, Löffler, H, Westerhausen, M, Leder, L D, Donhuijsen-Ant, R., Schadeck-Gressel, C., Schmidt, U., Löffler, H., Westerhausen, M., Leder, L. D. |
Abstract |
We present a case of acute megakaryoblastic leukemia identified by electron microscopy and platelet-specific antibodies. The histological examination of bone marrow showed distinct myelofibrosis. In accordance with recent communications, low-dose cytosine arabinoside treatment (20 mg twice daily s.c. over 21 days) was initiated. The subsequent bone marrow examination showed a severe hypoplasia with persistent blasts. Amsacrine and VP-16 were given without success. Finally the patient died of septicemia without proof of pathogen uninfluenced by antibiotic and antiseptic therapy 6 weeks after diagnosis. Our case report confirms the poor prognosis of acute megakaryoblastic leukemia. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 2 | 40% |
Other | 1 | 20% |
Unknown | 2 | 40% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 1 | 20% |
Agricultural and Biological Sciences | 1 | 20% |
Medicine and Dentistry | 1 | 20% |
Unknown | 2 | 40% |