Chapter title |
Overview.
|
---|---|
Chapter number | 12 |
Book title |
Heterogeneity in Asthma
|
Published in |
Advances in experimental medicine and biology, October 2013
|
DOI | 10.1007/978-1-4614-8603-9_12 |
Pubmed ID | |
Book ISBNs |
978-1-4614-8602-2, 978-1-4614-8603-9
|
Authors |
Wiktorowicz JE, John E. Wiktorowicz, Wiktorowicz, John E. |
Abstract |
Although broadly defined in the literature, for the purpose of this section, we define systems biology as the description of the dynamic genomic, proteomic, and metabolomic processes integrated into a functional model of the cell, organelle, or tissue that is capable of accurately tracking the biological system's response to environmental perturbations. The goal of this section is to complete the tripartite description of asthma systems biology, initiated by the previous section (Section II: Genetics and Genomics of Asthma), by reviewing the recent literature-the types and methods of sample collection, processing, analysis, and instrumentation-of metabolomic and proteomic investigations, including functional proteomic studies of the asthma innate immune response and glucocorticoid (GC) receptor signaling with reference to GC resistance in severe asthma. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Poland | 1 | 7% |
Unknown | 14 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 33% |
Researcher | 3 | 20% |
Student > Master | 3 | 20% |
Other | 1 | 7% |
Professor > Associate Professor | 1 | 7% |
Other | 1 | 7% |
Unknown | 1 | 7% |
Readers by discipline | Count | As % |
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Environmental Science | 3 | 20% |
Agricultural and Biological Sciences | 3 | 20% |
Psychology | 2 | 13% |
Economics, Econometrics and Finance | 1 | 7% |
Linguistics | 1 | 7% |
Other | 2 | 13% |
Unknown | 3 | 20% |