| Chapter title |
Genetic Evolution of Hepatitis E Virus
|
|---|---|
| Chapter number | 5 |
| Book title |
Hepatitis E Virus
|
| Published in |
Advances in experimental medicine and biology, January 2016
|
| DOI | 10.1007/978-94-024-0942-0_5 |
| Pubmed ID | |
| Book ISBNs |
978-9-40-240940-6, 978-9-40-240942-0
|
| Authors |
Yulin Zhang, Wanyun Gong, Hang Zeng, Ling Wang, Zhang, Yulin, Gong, Wanyun, Zeng, Hang, Wang, Ling |
| Abstract |
Comparative analysis of the genomic sequences of multiple hepatitis E virus (HEV) isolates has revealed extensive genomic diversity among them. Recently, a variety of genetically distinct HEV variants have also been isolated and identified from large numbers of animal species, including birds, rabbits, rats, ferrets, bats, cutthroat trout, and camels, among others. Furthermore, it has been reported that recombination in HEV genomes takes place in animals and in human patients. Also, chronic HEV infection in immunocompromised individuals has revealed the presence of viral strains carrying insertions from human genes. This paper reviews the current knowledge on the genomic variability and evolution of HEV. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 27% |
| Researcher | 2 | 18% |
| Student > Doctoral Student | 1 | 9% |
| Other | 1 | 9% |
| Student > Ph. D. Student | 1 | 9% |
| Other | 1 | 9% |
| Unknown | 2 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 3 | 27% |
| Agricultural and Biological Sciences | 2 | 18% |
| Medicine and Dentistry | 2 | 18% |
| Unknown | 4 | 36% |