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PEGylated Protein Drugs: Basic Science and Clinical Applications

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Cover of 'PEGylated Protein Drugs: Basic Science and Clinical Applications'

Table of Contents

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    Book Overview
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    Chapter 1 Preface PEGylated protein conjugates: A new class of therapeutics for the 21st century
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    Chapter 2 Protein PEGylation, basic science and biological applications
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    Chapter 3 Reactive PEGs for protein conjugation
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    Chapter 4 Rebridging disulphides: site-specific PEGylation by sequential bis-alkylation
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    Chapter 5 Enzymatic techniques for PEGylation of biopharmaceuticals
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    Chapter 6 The site-specific TGase-mediated PEGylation of proteins occurs at flexible sites
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    Chapter 7 Protein conjugates purification and characterization
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    Chapter 8 PEG and PEG conjugates toxicity: towards an understanding of the toxicity of PEG and its relevance to PEGylated biologicals
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    Chapter 9 The occurrence, induction, specificity and potential effect of antibodies against poly(ethylene glycol)
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    Chapter 10 Pegfilgrastim — designing an improved form of rmetHuG-CSF
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    Chapter 11 PEGylation of human growth hormone: strategies and properties
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    Chapter 12 PEGylated α interferons: two different strategies to achieve increased efficacy
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    Chapter 13 Development of PEGylated mammalian urate oxidase as a therapy for patients with refractory gout
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    Chapter 14 Certolizumab pegol: a PEGylated anti-tumour necrosis factor alpha biological agent
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    Chapter 15 PEG: a useful technology in anticancer therapy
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    Chapter 16 Regulatory strategy and approval processes considered for PEG-drug conjugates and other nanomedicines
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Title
PEGylated Protein Drugs: Basic Science and Clinical Applications
Published by
Birkhäuser Basel, December 2009
DOI 10.1007/978-3-7643-8679-5
ISBNs
978-3-76-438678-8, 978-3-76-438679-5
Editors

Veronese, Francesco M.

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X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 2%
Indonesia 1 <1%
Australia 1 <1%
Sweden 1 <1%
United Kingdom 1 <1%
United States 1 <1%
Unknown 122 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 33%
Researcher 18 14%
Student > Master 17 13%
Student > Bachelor 10 8%
Student > Doctoral Student 8 6%
Other 13 10%
Unknown 21 16%
Readers by discipline Count As %
Chemistry 23 18%
Biochemistry, Genetics and Molecular Biology 20 16%
Agricultural and Biological Sciences 18 14%
Engineering 10 8%
Materials Science 7 5%
Other 26 20%
Unknown 25 19%