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PEGylated Protein Drugs: Basic Science and Clinical Applications

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Cover of 'PEGylated Protein Drugs: Basic Science and Clinical Applications'

Table of Contents

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    Book Overview
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    Chapter 1 Preface PEGylated protein conjugates: A new class of therapeutics for the 21st century
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    Chapter 2 Protein PEGylation, basic science and biological applications
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    Chapter 3 Reactive PEGs for protein conjugation
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    Chapter 4 Rebridging disulphides: site-specific PEGylation by sequential bis-alkylation
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    Chapter 5 Enzymatic techniques for PEGylation of biopharmaceuticals
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    Chapter 6 The site-specific TGase-mediated PEGylation of proteins occurs at flexible sites
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    Chapter 7 Protein conjugates purification and characterization
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    Chapter 8 PEG and PEG conjugates toxicity: towards an understanding of the toxicity of PEG and its relevance to PEGylated biologicals
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    Chapter 9 The occurrence, induction, specificity and potential effect of antibodies against poly(ethylene glycol)
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    Chapter 10 Pegfilgrastim — designing an improved form of rmetHuG-CSF
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    Chapter 11 PEGylation of human growth hormone: strategies and properties
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    Chapter 12 PEGylated α interferons: two different strategies to achieve increased efficacy
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    Chapter 13 Development of PEGylated mammalian urate oxidase as a therapy for patients with refractory gout
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    Chapter 14 Certolizumab pegol: a PEGylated anti-tumour necrosis factor alpha biological agent
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    Chapter 15 PEG: a useful technology in anticancer therapy
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    Chapter 16 Regulatory strategy and approval processes considered for PEG-drug conjugates and other nanomedicines
Attention for Chapter 6: The site-specific TGase-mediated PEGylation of proteins occurs at flexible sites
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Citations

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Chapter title
The site-specific TGase-mediated PEGylation of proteins occurs at flexible sites
Chapter number 6
Book title
PEGylated Protein Drugs: Basic Science and Clinical Applications
Published by
Birkhäuser Basel, January 2009
DOI 10.1007/978-3-7643-8679-5_6
Book ISBNs
978-3-76-438678-8, 978-3-76-438679-5
Authors

Angelo Fontana, Barbara Spolaore, Anna Mero, Francesco M. Veronese

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 2 29%
Student > Master 2 29%
Unknown 3 43%
Readers by discipline Count As %
Chemistry 2 29%
Chemical Engineering 1 14%
Engineering 1 14%
Unknown 3 43%

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