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Mendeley readers
| Chapter title |
EBNA1
|
|---|---|
| Chapter number | 1 |
| Book title |
Epstein Barr Virus Volume 2
|
| Published in |
Current topics in microbiology and immunology, January 2015
|
| DOI | 10.1007/978-3-319-22834-1_1 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-922833-4, 978-3-31-922834-1
|
| Authors |
Lori Frappier |
| Abstract |
Epstein-Barr nuclear antigen 1 (EBNA1) plays multiple important roles in EBV latent infection and has also been shown to impact EBV lytic infection. EBNA1 is required for the stable persistence of the EBV genomes in latent infection and activates the expression of other EBV latency genes through interactions with specific DNA sequences in the viral episomes. EBNA1 also interacts with several cellular proteins to modulate the activities of multiple cellular pathways important for viral persistence and cell survival. These cellular effects are also implicated in oncogenesis, suggesting a direct role of EBNA1 in the development of EBV-associated tumors. |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 50 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 7 | 14% |
| Other | 4 | 8% |
| Student > Master | 4 | 8% |
| Researcher | 4 | 8% |
| Student > Ph. D. Student | 3 | 6% |
| Other | 4 | 8% |
| Unknown | 24 | 48% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 14 | 28% |
| Medicine and Dentistry | 4 | 8% |
| Agricultural and Biological Sciences | 3 | 6% |
| Immunology and Microbiology | 3 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 23 | 46% |