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X Demographics
Mendeley readers
Attention Score in Context
| Chapter title |
Spinocerebellar Ataxia Type 2
|
|---|---|
| Chapter number | 8 |
| Book title |
Polyglutamine Disorders
|
| Published in |
Advances in experimental medicine and biology, January 2018
|
| DOI | 10.1007/978-3-319-71779-1_8 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-971778-4, 978-3-31-971779-1
|
| Authors |
Daniel R. Scoles, Stefan M. Pulst |
| Abstract |
Spinocerebellar ataxia type 2 (SCA2) is autosomal dominantly inherited and caused by CAG repeat expansion in the ATXN2 gene. Because the CAG repeat expansion is localized to an encoded region of ATXN2, the result is an expanded polyglutamine (polyQ) tract in the ATXN2 protein. SCA2 is characterized by progressive ataxia, and slow saccades. No treatment for SCA2 exists. ATXN2 mutation causes gains of new or toxic functions for the ATXN2 protein, resulting in abnormally slow Purkinje cell (PC) firing frequency and ultimately PC loss. This chapter describes the characteristics of SCA2 patients briefly, and reviews ATXN2 molecular features and progress toward the identification of a treatment for SCA2. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 73 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 19% |
| Researcher | 8 | 11% |
| Student > Ph. D. Student | 7 | 10% |
| Student > Master | 5 | 7% |
| Student > Doctoral Student | 2 | 3% |
| Other | 7 | 10% |
| Unknown | 30 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 14 | 19% |
| Medicine and Dentistry | 9 | 12% |
| Neuroscience | 7 | 10% |
| Agricultural and Biological Sciences | 4 | 5% |
| Computer Science | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 32 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#14,165,787
of 22,703,044 outputs
Outputs from Advances in experimental medicine and biology
#2,077
of 4,906 outputs
Outputs of similar age
#238,489
of 440,589 outputs
Outputs of similar age from Advances in experimental medicine and biology
#77
of 237 outputs
Altmetric has tracked 22,703,044 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,906 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,589 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 237 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.