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Pseudogenes

Overview of attention for book
Cover of 'Pseudogenes'

Table of Contents

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    Book Overview
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    Chapter 1 Pseudogene Redux with New Biological Significance
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    Chapter 2 Contribution of Pseudogenes to Sequence Diversity
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    Chapter 3 Computational Methods for Pseudogene Annotation Based on Sequence Homology
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    Chapter 4 Computational Methods of Identification of Pseudogenes Based on Functionality: Entropy and GC Content.
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    Chapter 5 Methods of Identification of Pseudogenes Based on Functionality: Hybridization of 18S rRNA and mRNA During Translation
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    Chapter 6 Whole-Genome Identification of Neutrally Evolving Pseudogenes Using the Evolutionary Measure dN/dS
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    Chapter 7 Methods to study the occurrence and the evolution of pseudogenes through a phylogenetic approach.
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    Chapter 8 Methods for Detecting Transcribed Pseudogenes: PCR on Regions of High Sequence Similarity Followed by Cloning and Sequencing
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    Chapter 9 RNA Amplification for Pseudogene Detection Using RNA-Seq.
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    Chapter 10 GENCODE Pseudogenes
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    Chapter 11 Methods to Detect Transcribed Pseudogenes: RNA-Seq Discovery Allows Learning Through Features
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    Chapter 12 Proteomics techniques for the detection of translated pseudogenes.
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    Chapter 13 Pseudogenes as Competitive Endogenous RNAs: Target Prediction and Validation.
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    Chapter 14 Pseudogenes: A Novel Source of trans-Acting Antisense RNAs
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    Chapter 15 Pseudogene-Derived Endogenous siRNAs and Their Function
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    Chapter 16 Methods to Study Translated Pseudogenes: In Vitro Translation, Fusion with a Tag/Reporter Gene, and Complementation Assay
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    Chapter 17 Targeted and robust amplification of mitochondrial DNA in the presence of nuclear-encoded mitochondrial pseudogenes using φ29 DNA polymerases.
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    Chapter 18 Pseudogenes
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    Chapter 19 Mutational Analysis of CYP21A2 Gene and CYP21A1P Pseudogene: Long-range PCR on Genomic DNA.
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    Chapter 20 PMS2 Gene Mutational Analysis: Direct cDNA Sequencing to Circumvent Pseudogene Interference
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    Chapter 21 Dealing with Pseudogenes in Molecular Diagnostics in the Next-Generation Sequencing Era
Attention for Chapter 12: Proteomics techniques for the detection of translated pseudogenes.
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Chapter title
Proteomics techniques for the detection of translated pseudogenes.
Chapter number 12
Book title
Pseudogenes
Published in
Methods in molecular biology, April 2014
DOI 10.1007/978-1-4939-0835-6_12
Pubmed ID
24823778
Book ISBNs
978-1-4939-0834-9, 978-1-4939-0835-6
Authors

Ucciferri N, Rocchiccioli S, Nadia Ucciferri, Silvia Rocchiccioli Ph.D., Silvia Rocchiccioli

Editors

Laura Poliseno

Abstract

Increasing evidence indicates that pseudogenes can reach the translational process. Translated pseudogene products have in fact been found in various organisms, confuting the original definition of pseudogenes as genes without any coding potential. Proteomics is the main technology allowing the study of proteins and, when integrated with genomics, is defined as proteogenomics. In proteogenomics, the peptide-genome alignment drives the identification and annotation of gene products and allows for a better understanding of their function. In this chapter, we give a brief overview of the proteomic techniques applied to pseudogenes. In particular, we discuss peptide spectrum acquisition, mass data analysis, and genome database matching.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 7%
Unknown 13 93%

Demographic breakdown

Readers by professional status Count As %
Other 3 21%
Student > Ph. D. Student 3 21%
Professor > Associate Professor 2 14%
Researcher 2 14%
Student > Doctoral Student 1 7%
Other 0 0%
Unknown 3 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 29%
Agricultural and Biological Sciences 2 14%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Immunology and Microbiology 1 7%
Chemistry 1 7%
Other 1 7%
Unknown 4 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2018.
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#20,249,662
of 22,778,347 outputs
Outputs from Methods in molecular biology
#9,869
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Outputs of similar age
#193,324
of 227,134 outputs
Outputs of similar age from Methods in molecular biology
#95
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