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Non-canonical Cyclic Nucleotides

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Cover of 'Non-canonical Cyclic Nucleotides'

Table of Contents

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    Book Overview
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    Chapter 34 Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites
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    Chapter 35 Cyclic Nucleotide Monophosphates in Plants and Plant Signaling.
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    Chapter 36 cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase as Cyclic Nucleotide Effectors
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    Chapter 37 Interaction of Epac with Non-canonical Cyclic Nucleotides
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    Chapter 38 Identification of cCMP and cUMP Substrate Proteins and Cross Talk Between cNMPs.
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    Chapter 39 3',5'-cIMP as Potential Second Messenger in the Vascular Wall.
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    Chapter 40 Discovery and Roles of 2′,3′-cAMP in Biological Systems
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    Chapter 41 Medicinal Chemistry of the Noncanonical Cyclic Nucleotides cCMP and cUMP
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    Chapter 42 Holistic Methods for the Analysis of cNMP Effects
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    Chapter 43 The Chemistry of the Noncanonical Cyclic Dinucleotide 2′3′-cGAMP and Its Analogs
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    Chapter 5000 8-Nitro-cGMP: A Novel Protein-Reactive cNMP and Its Emerging Roles in Autophagy
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    Chapter 5001 Mass Spectrometric Analysis of Non-canonical Cyclic Nucleotides
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    Chapter 5002 Cyclic Dinucleotides in the Scope of the Mammalian Immune System
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    Chapter 5003 The Pseudomonas aeruginosa Exoenzyme Y: A Promiscuous Nucleotidyl Cyclase Edema Factor and Virulence Determinant
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    Chapter 5004 Inactivation of Non-canonical Cyclic Nucleotides: Hydrolysis and Transport
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    Chapter 5005 cCMP and cUMP Across the Tree of Life: From cCMP and cUMP Generators to cCMP- and cUMP-Regulated Cell Functions
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    Chapter 5006 Regulation of HCN Ion Channels by Non-canonical Cyclic Nucleotides
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    Chapter 5007 cCMP and cUMP in Apoptosis: Concepts and Methods
Attention for Chapter 38: Identification of cCMP and cUMP Substrate Proteins and Cross Talk Between cNMPs.
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Chapter title
Identification of cCMP and cUMP Substrate Proteins and Cross Talk Between cNMPs.
Chapter number 38
Book title
Non-canonical Cyclic Nucleotides
Published in
Handbook of experimental pharmacology, January 2016
DOI 10.1007/164_2015_38
Pubmed ID
Book ISBNs
978-3-31-952671-3, 978-3-31-952673-7
Authors

Schlossmann, Jens, Wolfertstetter, Stefanie, Jens Schlossmann, Stefanie Wolfertstetter

Abstract

cCMP and cUMP are pyrimidine cyclic nucleotides which are present in several types of cells. These molecules could exert diverse cellular functions and might act as second messengers. In the last years, diverse approaches were performed to analyze possible cellular substrates and signaling pathways of cCMP and cUMP. In this review these approaches are summarized, and probable cross talk of these signaling molecules is described. These analyses might lead to the (patho)physiological and pharmacological relevance of these noncanonical cyclic nucleotides.

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The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 1 100%
Researcher 1 100%
Readers by discipline Count As %
Unspecified 1 100%
Biochemistry, Genetics and Molecular Biology 1 100%