Chapter title |
Estimating Heritability from Twin Studies
|
---|---|
Chapter number | 9 |
Book title |
Statistical Human Genetics
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7274-6_9 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7273-9, 978-1-4939-7274-6
|
Authors |
Katrina L. Grasby, Karin J. H. Verweij, Miriam A. Mosing, Brendan P. Zietsch, Sarah E. Medland, Grasby, Katrina L., Verweij, Karin J. H., Mosing, Miriam A., Zietsch, Brendan P., Medland, Sarah E. |
Abstract |
This chapter describes how the heritability of a trait can be estimated using data collected from pairs of twins. The principles of the classical twin design are described, followed by the assumptions, and some possible extensions of the design. In the second part of this chapter, two example scripts are presented and the basic steps for estimating heritability using the statistical program OpenMx are explained. OpenMx and the scripts used for this chapter can be downloaded so that readers can adapt and use the scripts for their own purposes. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 18% |
Student > Ph. D. Student | 6 | 18% |
Student > Bachelor | 4 | 12% |
Student > Master | 4 | 12% |
Professor | 3 | 9% |
Other | 7 | 21% |
Unknown | 4 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 18% |
Biochemistry, Genetics and Molecular Biology | 5 | 15% |
Psychology | 5 | 15% |
Agricultural and Biological Sciences | 4 | 12% |
Neuroscience | 3 | 9% |
Other | 5 | 15% |
Unknown | 6 | 18% |