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Hepatitis E Virus

Overview of attention for book
Attention for Chapter 8: HEV Cell Culture
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Chapter title
HEV Cell Culture
Chapter number 8
Book title
Hepatitis E Virus
Published in
Advances in experimental medicine and biology, January 2016
DOI 10.1007/978-94-024-0942-0_8
Pubmed ID
Book ISBNs
978-9-40-240940-6, 978-9-40-240942-0
Authors

Feng Zhang, Youchun Wang, Zhang, Feng, Wang, Youchun

Abstract

Cell culture is an important research method in virology. Although many attempts were tried to culture HEV in cells, only two cell culture systems were considered to have high enough efficient for usage. Concentration of virus stocks, host cells, and medium components affect the culture efficient, and the genetic mutations during HEV passage were found to be associated with the increased virulence in cell culture. As an alternative method for traditional cell culture, the infectious cDNA clones were constructed. The viral thermal stability, factors that impact the host range, posttranslation of viral proteins and function of different viral protein were studied using the infectious cDNA clones. The studies on progeny virus showed that the virus secreted from host cells have an envelope, and its formation was associated with pORF3. This result explained the phenomenon that virus could infect hosts cells in the presence of anti-HEV antibodies.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 44%
Student > Ph. D. Student 2 22%
Student > Bachelor 1 11%
Professor 1 11%
Unknown 1 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 22%
Medicine and Dentistry 2 22%
Immunology and Microbiology 1 11%
Agricultural and Biological Sciences 1 11%
Unknown 3 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2017.
All research outputs
#18,572,036
of 23,002,898 outputs
Outputs from Advances in experimental medicine and biology
#3,325
of 4,961 outputs
Outputs of similar age
#285,600
of 394,604 outputs
Outputs of similar age from Advances in experimental medicine and biology
#285
of 444 outputs
Altmetric has tracked 23,002,898 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,961 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,604 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 444 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.