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Centromeres and Kinetochores

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Cover of 'Centromeres and Kinetochores'

Table of Contents

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    Book Overview
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    Chapter 1 Use of Mass Spectrometry to Study the Centromere and Kinetochore
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    Chapter 2 Critical Foundation of the Kinetochore: The Constitutive Centromere-Associated Network (CCAN)
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    Chapter 3 The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function
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    Chapter 4 Centrochromatin of Fungi
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    Chapter 5 Evolutionary Lessons from Species with Unique Kinetochores
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    Chapter 6 Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to Maintain Centromere Homeostasis
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    Chapter 7 Orchestrating the Specific Assembly of Centromeric Nucleosomes
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    Chapter 8 Artificial Chromosomes and Strategies to Initiate Epigenetic Centromere Establishment
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    Chapter 9 Post-translational Modifications of Centromeric Chromatin
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    Chapter 10 Centromere Silencing Mechanisms
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    Chapter 11 Centromere Transcription: Means and Motive
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    Chapter 12 The Promises and Challenges of Genomic Studies of Human Centromeres
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    Chapter 13 DNA Sequences in Centromere Formation and Function
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    Chapter 14 The Unique DNA Sequences Underlying Equine Centromeres
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    Chapter 15 Centromere Dynamics in Male and Female Germ Cells
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    Chapter 16 Cell Biology of Cheating—Transmission of Centromeres and Other Selfish Elements Through Asymmetric Meiosis
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    Chapter 17 Biophysics of Microtubule End Coupling at the Kinetochore
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    Chapter 18 Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing
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    Chapter 19 A Kinase-Phosphatase Network that Regulates Kinetochore-Microtubule Attachments and the SAC
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    Chapter 20 Centromeric Cohesin: Molecular Glue and Much More
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    Chapter 21 Centromere Structure and Function
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    Chapter 22 The Role of Centromere Defects in Cancer
Attention for Chapter 9: Post-translational Modifications of Centromeric Chromatin
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Chapter title
Post-translational Modifications of Centromeric Chromatin
Chapter number 9
Book title
Centromeres and Kinetochores
Published in
Progress in molecular and subcellular biology, August 2017
DOI 10.1007/978-3-319-58592-5_9
Pubmed ID
Book ISBNs
978-3-31-958591-8, 978-3-31-958592-5
Authors

Ana García del Arco, Sylvia Erhardt

Abstract

Regulation of chromatin structures is important for the control of DNA processes such as gene expression, and misregulation of chromatin is implicated in diverse diseases. Covalent post-translational modifications of histones are a prominent way to regulate chromatin structure and different chromatin regions bear their specific signature of histone modifications. The composition of centromeric chromatin is significantly different from other chromatin structures and mainly defined by the presence of the histone H3-variant CENP-A. Here we summarize the composition of centromeric chromatin and what we know about its differential regulation by post-translational modifications.

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Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 25%
Professor 1 13%
Unspecified 1 13%
Researcher 1 13%
Student > Bachelor 1 13%
Other 0 0%
Unknown 2 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 38%
Unspecified 1 13%
Agricultural and Biological Sciences 1 13%
Earth and Planetary Sciences 1 13%
Unknown 2 25%