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Chapter title |
Characterization of Extracellular Vesicles by Surface Plasmon Resonance
|
---|---|
Chapter number | 11 |
Book title |
Extracellular Vesicles
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Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7253-1_11 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7251-7, 978-1-4939-7253-1
|
Authors |
Hyungsoon Im, Katherine Yang, Hakho Lee, Cesar M. Castro |
Abstract |
Surface plasmon resonance (SPR ) enables real-time, label-free detection of ligand binding to target receptors immobilized on a sensing surface. SPR has emerged as a promising technique for extracellular vesicle (EV) characterization with its label-free detection scheme, and exquisite sensitivity. Among the various system configurations, nanohole-based SPR sensors are of particular interest because of their simple optical setup, tunability, and scalability. Here, we describe the characterization of circulating EVs or exosomes from human clinical samples using a nanohole-based SPR sensor, named nPLEX (nano-plasmonic exosome) sensing. |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 36% |
Other | 3 | 14% |
Researcher | 3 | 14% |
Professor | 1 | 5% |
Student > Master | 1 | 5% |
Other | 1 | 5% |
Unknown | 5 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 4 | 18% |
Biochemistry, Genetics and Molecular Biology | 2 | 9% |
Agricultural and Biological Sciences | 2 | 9% |
Physics and Astronomy | 2 | 9% |
Medicine and Dentistry | 2 | 9% |
Other | 4 | 18% |
Unknown | 6 | 27% |