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Mitochondrial DNA

Overview of attention for book
Cover of 'Mitochondrial DNA'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Comprehensive Mitochondrial Genome Analysis by Massively Parallel Sequencing.
  3. Altmetric Badge
    Chapter 2 Mitochondrial DNA
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    Chapter 3 Quantification of DNA Damage by Real-Time qPCR
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    Chapter 4 Quantitation of Mitochondrial DNA Deletions Via Restriction Digestion/Long-Range Single-Molecule PCR
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    Chapter 5 A Single-Cell Resolution Imaging Protocol of Mitochondrial DNA Dynamics in Physiopathology, mTRIP, Which Also Evaluates Sublethal Cytotoxicity.
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    Chapter 6 Scalable Isolation of Mammalian Mitochondria for Nucleic Acid and Nucleoid Analysis
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    Chapter 7 Tracking Mitochondrial DNA In Situ
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    Chapter 8 Analysis of Replicating Mitochondrial DNA by In Organello Labeling and Two-Dimensional Agarose Gel Electrophoresis
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    Chapter 9 Translation and Assembly of Radiolabeled Mitochondrial DNA-Encoded Protein Subunits from Cultured Cells and Isolated Mitochondria
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    Chapter 10 Analysis of Mitochondrial DNA Copy Number and Its Regulation Through DNA Methylation of POLGA
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    Chapter 11 Engineered mtZFNs for Manipulation of Human Mitochondrial DNA Heteroplasmy
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    Chapter 12 Mitochondrial DNA
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    Chapter 13 Import of Fluorescent RNA into Mitochondria of Living Cells
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    Chapter 14 Purification and Comparative Assay of the Human Mitochondrial Replicative DNA Helicase
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    Chapter 15 Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster.
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    Chapter 16 Mitochondrial DNA
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    Chapter 17 Biolayer Interferometry: A Novel Method to Elucidate Protein–Protein and Protein–DNA Interactions in the Mitochondrial DNA Replisome
  19. Altmetric Badge
    Chapter 18 ERRATUM TO: Quantitation of Mitochondrial DNA Deletions Via Restriction Digestion/Long-Range Single-Molecule PCR
Attention for Chapter 1: Comprehensive Mitochondrial Genome Analysis by Massively Parallel Sequencing.
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Chapter title
Comprehensive Mitochondrial Genome Analysis by Massively Parallel Sequencing.
Chapter number 1
Book title
Mitochondrial DNA
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3040-1_1
Pubmed ID
Book ISBNs
978-1-4939-3039-5, 978-1-4939-3040-1
Authors

Palculict, Meagan E, Zhang, Victor Wei, Wong, Lee-Jun, Wang, Jing, Meagan E. Palculict, Victor Wei Zhang, Lee-Jun Wong, Jing Wang

Abstract

Next-generation sequencing (NGS) based on massively parallel sequencing (MPS) of the entire 16,569 bp mitochondrial genome generates thousands of reads for each nucleotide position. The high-throughput sequence data generated allow the detection of mitochondrial DNA (mtDNA) point mutations and deletions with the ability to accurately quantify the mtDNA point mutation heteroplasmy and to determine the deletion breakpoints. In addition, this method is particularly sensitive for the detection of low-level mtDNA large deletions and multiple deletions. It is by far the most powerful tool for molecular diagnosis of mtDNA disorders.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 5 22%
Researcher 4 17%
Student > Bachelor 3 13%
Student > Doctoral Student 2 9%
Other 1 4%
Other 3 13%
Unknown 5 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 39%
Agricultural and Biological Sciences 4 17%
Neuroscience 2 9%
Veterinary Science and Veterinary Medicine 1 4%
Medicine and Dentistry 1 4%
Other 1 4%
Unknown 5 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2016.
All research outputs
#18,159,399
of 23,327,904 outputs
Outputs from Methods in molecular biology
#7,413
of 13,337 outputs
Outputs of similar age
#270,617
of 396,143 outputs
Outputs of similar age from Methods in molecular biology
#759
of 1,474 outputs
Altmetric has tracked 23,327,904 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,337 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,143 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,474 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.