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Molecular Toxicology Protocols

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Cover of 'Molecular Toxicology Protocols'

Table of Contents

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    Book Overview
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    Chapter 1 Array-Based Immunoassays with Rolling-Circle Amplification Detection
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    Chapter 2 Analysis of protein changes using two-dimensional difference gel electrophoresis.
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    Chapter 3 Assessment of pathological and physiological changes in mouse lung through bronchoalveolar lavage.
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    Chapter 4 Analysis of clinical and biological samples using microsphere-based multiplexing luminex system.
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    Chapter 5 Detection of DNA Methylation by MeDIP and MBDCap Assays: An Overview of Techniques.
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    Chapter 6 Screening of DNA Methylation Changes by Methylation-Sensitive Random Amplified Polymorphic DNA-Polymerase Chain Reaction (MS-RAPD-PCR)
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    Chapter 7 Strategies for Measurement of Biotransformation Enzyme Gene Expression
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    Chapter 8 Genotyping Technologies: Application to Biotransformation Enzyme Genetic Polymorphism Screening
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    Chapter 9 TaqMan™ Fluorogenic Detection System to Analyze Gene Transcription in Autopsy Material
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    Chapter 10 32P-Postlabeling Analysis of DNA Adducts
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    Chapter 11 Modification of the 32P-Postlabeling Method to Detect a Single Adduct Species as a Single Spot
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    Chapter 12 DNA Isolation and Sample Preparation for Quantification of Adduct Levels by Accelerator Mass Spectrometry
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    Chapter 13 Analysis of DNA Strand Cleavage at Abasic Sites
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    Chapter 14 Premature chromosome condensation in human resting peripheral blood lymphocytes without mitogen stimulation for chromosome aberration analysis using specific whole chromosome DNA hybridization probes.
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    Chapter 15 Mutagen Sensitivity as Measured by Induced Chromatid Breakage as a Marker of Cancer Risk
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    Chapter 16 Pulsed-Field Gel Electrophoresis Analysis of Multicellular DNA Double-Strand Break Damage and Repair
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    Chapter 17 Detection of Pig-a Mutant Erythrocytes in the Peripheral Blood of Rats and Mice
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    Chapter 18 The Blood-Based Glycophorin A (GPA) Human In Vivo Somatic Mutation Assay
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    Chapter 19 Flow Cytometric Quantification of Mutant T Cells with Altered Expression of the T-Cell Receptor: Detecting Somatic Mutants in Humans and Mice
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    Chapter 20 Analysis of In Vivo Mutation in the Hprt and Tk Genes of Mouse Lymphocytes
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    Chapter 21 Quantifying In Vivo Somatic Mutations Using Transgenic Mouse Model Systems
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    Chapter 22 The Human T-Cell Cloning Assay: Identifying Genotypes Susceptible to Drug Toxicity and Somatic Mutation
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    Chapter 23 Molecular Analysis of Mutations in the Human HPRT Gene.
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    Chapter 24 Simultaneous Quantification of t(14;18) and HPRT Exon 2/3 Deletions in Human Lymphocytes
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    Chapter 25 Mutation Screening of the TP53 Gene by Temporal Temperature Gel Electrophoresis (TTGE)
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    Chapter 26 Detection of Point Mutations of K-ras Oncogene and p53 Tumor-Suppressor Gene in Sputum Samples
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    Chapter 27 ACB-PCR Quantification of Somatic Oncomutation
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    Chapter 28 Gel-Based Nonradioactive Single-Strand Conformational Polymorphism and Mutation Detection: Limitations and Solutions
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    Chapter 29 Detection and characterization of oncogene mutations in preneoplastic and early neoplastic lesions.
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    Chapter 30 Detection of DNA Double-Strand Breaks and Chromosome Translocations Using Ligation-Mediated PCR and Inverse PCR
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    Chapter 31 Quantitative PCR-Based Measurement of Nuclear and Mitochondrial DNA Damage and Repair in Mammalian Cells.
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    Chapter 32 The Sister Chromatid Exchange (SCE) Assay.
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    Chapter 33 The Gene Cluster Instability (GCI) Assay for Recombination
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    Chapter 34 Measuring Recombination Proficiency in Mouse Embryonic Stem Cells
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    Chapter 35 Microsatellite Instability: An Indirect Assay to Detect Defects in the Cellular Mismatch Repair Machinery
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    Chapter 36 Unscheduled DNA Synthesis: The Clinical and Functional Assay for Global Genomic DNA Nucleotide Excision Repair
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    Chapter 37 Analysis of Actively Transcribed DNA Repair Using a Transfection-Based System
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    Chapter 38 Molecular Toxicology Protocols
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    Chapter 39 Analysis of Double-Strand Break Repair by Nonhomologous DNA End Joining in Cell-Free Extracts from Mammalian Cells
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    Chapter 40 Bioenergetic Analysis of Intact Mammalian Cells Using the Seahorse XF24 Extracellular Flux Analyzer and a Luciferase ATP Assay
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    Chapter 41 Quantification of selective phosphatidylserine oxidation during apoptosis.
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    Chapter 42 Quantitative Method of Measuring Phosphatidylserine Externalization During Apoptosis Using Electron Paramagnetic Resonance (EPR) Spectroscopy and Annexin-Conjugated Iron.
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    Chapter 43 Detection of Programmed Cell Death in Cells Exposed to Genotoxic Agents Using a Caspase Activation Assay
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Title
Molecular Toxicology Protocols
Published by
Humana Press, January 2014
DOI 10.1007/978-1-62703-739-6
ISBNs
978-1-62703-738-9, 978-1-62703-739-6
Editors

Phouthone Keohavong, Stephen G. Grant

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X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Student > Master 5 16%
Researcher 5 16%
Student > Bachelor 3 10%
Professor > Associate Professor 3 10%
Other 4 13%
Unknown 5 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 39%
Agricultural and Biological Sciences 3 10%
Environmental Science 2 6%
Veterinary Science and Veterinary Medicine 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 6 19%
Unknown 6 19%