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Sphingosine-1-Phosphate

Overview of attention for book
Cover of 'Sphingosine-1-Phosphate'

Table of Contents

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    Book Overview
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    Chapter 3 Sphingosine-1-Phosphate (S1P) Signaling in Neural Progenitors
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    Chapter 4 Maintenance of Human Embryonic Stem Cells by Sphingosine-1-Phosphate and Platelet-Derived Growth Factor
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    Chapter 5 Measuring Sphingosine-1-Phosphate/Protein Interactions with the Kinetic Exclusion Assay
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    Chapter 6 A Cleanup Method for Mass Spectrometric Analysis of Sphingosine- and Ceramide-1-Phosphate in Blood and Solid Tissue Using a Phosphate Capture Molecule
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    Chapter 23 3D Stacked Construct: A Novel Substitute for Corneal Tissue Engineering
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    Chapter 24 Analysis of S1P Receptor Expression by Uterine Immune Cells Using Standardized Multi-parametric Flow Cytometry
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    Chapter 25 A Rapid Fluorescence Assay for Measuring Sphingosine-1-Phosphate Transporter Activity in Erythrocytes
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    Chapter 26 S1P Synergizes with Wall Shear Stress and Other Angiogenic Factors to Induce Endothelial Cell Sprouting Responses
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    Chapter 41 An Improved Isoform-Selective Assay for Sphingosine Kinase 1 Activity
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    Chapter 42 Methods for Analyzing Sphingosine-1-Phosphate Signaling in Human and Mouse Primary Mast Cells
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    Chapter 43 Ceramide and S1P Signaling in Embryonic Stem Cell Differentiation
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    Chapter 44 Immunohistochemical Detection of Sphingosine-1-Phosphate and Sphingosine Kinase-1 in Human Tissue Samples and Cell Lines
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    Chapter 51 In Vitro Methods to Study the Modulation of Migration and Invasion by Sphingosine-1-Phosphate
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    Chapter 55 Measurement of Lysophosphatidic Acid and Sphingosine-1-Phosphate by Liquid Chromatography-Coupled Electrospray Ionization Tandem Mass Spectrometry
Attention for Chapter 43: Ceramide and S1P Signaling in Embryonic Stem Cell Differentiation
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

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Chapter title
Ceramide and S1P Signaling in Embryonic Stem Cell Differentiation
Chapter number 43
Book title
Methods in Molecular Biology
Published in
Methods in molecular biology, May 2017
DOI 10.1007/7651_2017_43
Pubmed ID
Book ISBNs
978-1-4939-7412-2, 978-1-4939-7413-9
Authors

Guanghu Wang, Stefka D. Spassieva, Erhard Bieberich

Abstract

Bioactive sphingolipids are important regulators for stem cell survival and differentiation. Most recently, we have coined the term "morphogenetic lipids" for sphingolipids that regulate stem cells during embryonic and postnatal development. The sphingolipid ceramide and its derivative, sphingosine-1-phosphate (S1P), can act synergistically as well as antagonistically on embryonic stem (ES) cell differentiation. We show here simple as well as state-of-the-art methods to analyze sphingolipids in differentiating ES cells and discuss new protocols to use ceramide and S1P analogs for the guided differentiation of mouse ES cells toward neuronal and glial lineage.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 47%
Student > Bachelor 3 18%
Researcher 2 12%
Student > Master 2 12%
Unknown 2 12%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 41%
Veterinary Science and Veterinary Medicine 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Agricultural and Biological Sciences 1 6%
Neuroscience 1 6%
Other 1 6%
Unknown 5 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2017.
All research outputs
#3,659,839
of 22,977,819 outputs
Outputs from Methods in molecular biology
#904
of 13,147 outputs
Outputs of similar age
#65,596
of 313,676 outputs
Outputs of similar age from Methods in molecular biology
#14
of 261 outputs
Altmetric has tracked 22,977,819 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,147 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,676 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 261 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.