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Reverse Genetics of RNA Viruses

Overview of attention for book
Attention for Chapter 1: Reverse Genetics for Mammalian Orthoreovirus
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Chapter title
Reverse Genetics for Mammalian Orthoreovirus
Chapter number 1
Book title
Reverse Genetics of RNA Viruses
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6964-7_1
Pubmed ID
Book ISBNs
978-1-4939-6962-3, 978-1-4939-6964-7
Authors

Johnasha D. Stuart, Matthew B. Phillips, Karl W. Boehme, Stuart, Johnasha D., Phillips, Matthew B., Boehme, Karl W.

Editors

Daniel R. Perez

Abstract

Reverse genetics allows introduction of specific alterations into a viral genome. Studies performed with mutant viruses generated using reverse genetics approaches have contributed immeasurably to our understanding of viral replication and pathogenesis, and also have led to development of novel vaccines and virus-based vectors. Here, we describe the reverse genetics system that allows for production and recovery of mammalian orthoreovirus, a double-stranded (ds) RNA virus, from plasmids that encode the viral genome.

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Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Librarian 1 33%
Student > Ph. D. Student 1 33%
Student > Master 1 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 33%
Agricultural and Biological Sciences 1 33%
Medicine and Dentistry 1 33%