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High Pressure Bioscience : Basic Concepts, Applications and Frontiers

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Cover of 'High Pressure Bioscience : Basic Concepts, Applications and Frontiers'

Table of Contents

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    Book Overview
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    Chapter 1 Early Days of Pressure Denaturation Studies of Proteins
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    Chapter 2 Protein Denaturation on p - T Axes – Thermodynamics and Analysis
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    Chapter 3 Driving Forces in Pressure-Induced Protein Transitions
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    Chapter 4 Why and How Does Pressure Unfold Proteins?
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    Chapter 5 Volume and Compressibility of Proteins
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    Chapter 6 High Pressure Bioscience
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    Chapter 7 Water Turns the “Non-biological” Fluctuation of Protein into “Biological” One
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    Chapter 8 Pressure Effects on the Intermolecular Interaction Potential of Condensed Protein Solutions
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    Chapter 9 High Pressure NMR Methods for Characterizing Functional Substates of Proteins
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    Chapter 10 High-Pressure NMR Spectroscopy Reveals Functional Sub-states of Ubiquitin and Ubiquitin-Like Proteins
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    Chapter 11 Functional Sub-states by High-pressure Macromolecular Crystallography
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    Chapter 12 Cavities and Excited States in Proteins
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    Chapter 13 Exploring the Protein Folding Pathway with High-Pressure NMR: Steady-State and Kinetics Studies
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    Chapter 14 Basic Equations in Statics and Kinetics of Protein Polymerization and the Mechanism of the Formation and Dissociation of Amyloid Fibrils Revealed by Pressure Perturbation
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    Chapter 15 Pressure-Inactivated Virus: A Promising Alternative for Vaccine Production
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    Chapter 16 How Do Membranes Respond to Pressure?
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    Chapter 17 Pressure Effects on Artificial and Cellular Membranes
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    Chapter 18 Effects of High Hydrostatic Pressure on Microbial Cell Membranes: Structural and Functional Perspectives.
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    Chapter 19 Homeoviscous Adaptation of Membranes in Archaea.
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    Chapter 20 Pressure-Dependent Gene Activation in Yeast Cells.
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    Chapter 21 Environmental Adaptation of Dihydrofolate Reductase from Deep-Sea Bacteria.
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    Chapter 22 Moss Spores Can Tolerate Ultra-high Pressure.
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    Chapter 23 Pressure-Based Strategy for the Inactivation of Spores
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    Chapter 24 Use of Pressure Activation in Food Quality Improvement
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    Chapter 25 Use of Pressure for Improving Storage Quality of Fresh-Cut Produce.
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    Chapter 26 Application of High-Pressure Treatment to Enhancement of Functional Components in Agricultural Products and Development of Sterilized Foods
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    Chapter 27 High-Pressure Microscopy for Studying Molecular Motors.
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    Chapter 28 Ion Channels Activated by Mechanical Forces in Bacterial and Eukaryotic Cells
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    Chapter 29 Gravitational Effects on Human Physiology.
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    Chapter 30 High Pressure Small-Angle X-Ray Scattering
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    Chapter 31 High Pressure Macromolecular Crystallography
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    Chapter 32 High-Pressure Fluorescence Spectroscopy.
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    Chapter 33 High Pressure NMR Spectroscopy
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    Chapter 34 Erratum
Attention for Chapter 4: Why and How Does Pressure Unfold Proteins?
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Citations

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Chapter title
Why and How Does Pressure Unfold Proteins?
Chapter number 4
Book title
High Pressure Bioscience
Published in
Sub cellular biochemistry, January 2015
DOI 10.1007/978-94-017-9918-8_4
Pubmed ID
Book ISBNs
978-9-40-179917-1, 978-9-40-179918-8
Authors

Catherine A. Royer, Royer, Catherine A.

Abstract

This year, 2014, marks the 100th anniversary of the first publication reporting the denaturation of proteins by high hydrostatic pressure (Bridgman 1914). Since that time a large and recently increasing number of studies of pressure effects on protein stability have been published, yet the mechanism for the action of pressure on proteins remains subject to considerable debate. This review will present an overview from this author's perspective of where this debate stands today.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 38%
Professor 2 15%
Researcher 2 15%
Unspecified 1 8%
Student > Postgraduate 1 8%
Other 0 0%
Unknown 2 15%
Readers by discipline Count As %
Chemistry 3 23%
Agricultural and Biological Sciences 2 15%
Biochemistry, Genetics and Molecular Biology 1 8%
Chemical Engineering 1 8%
Medicine and Dentistry 1 8%
Other 1 8%
Unknown 4 31%