| Chapter title |
Functional Sub-states by High-pressure Macromolecular Crystallography
|
|---|---|
| Chapter number | 11 |
| Book title |
High Pressure Bioscience
|
| Published in |
Sub cellular biochemistry, January 2015
|
| DOI | 10.1007/978-94-017-9918-8_11 |
| Pubmed ID | |
| Book ISBNs |
978-9-40-179917-1, 978-9-40-179918-8
|
| Authors |
Anne-Claire Dhaussy, Eric Girard, Dhaussy, Anne-Claire, Girard, Eric |
| Abstract |
At the molecular level, high-pressure perturbation is of particular interest for biological studies as it allows trapping conformational substates. Moreover, within the context of high-pressure adaptation of deep-sea organisms, it allows to decipher the molecular determinants of piezophily. To provide an accurate description of structural changes produced by pressure in a macromolecular system, developments have been made to adapt macromolecular crystallography to high-pressure studies. The present chapter is an overview of results obtained so far using high-pressure macromolecular techniques, from nucleic acids to virus capsid through monomeric as well as multimeric proteins. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor | 1 | 20% |
| Student > Bachelor | 1 | 20% |
| Researcher | 1 | 20% |
| Other | 1 | 20% |
| Unknown | 1 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 2 | 40% |
| Biochemistry, Genetics and Molecular Biology | 1 | 20% |
| Unknown | 2 | 40% |