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Mendeley readers
Chapter title |
Fowl Adenovirus-Based Vaccine Platform
|
---|---|
Chapter number | 3 |
Book title |
Recombinant Virus Vaccines
|
Published in |
Methods in molecular biology, April 2017
|
DOI | 10.1007/978-1-4939-6869-5_3 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6867-1, 978-1-4939-6869-5
|
Authors |
Juan C. Corredor, Yanlong Pei, Éva Nagy |
Editors |
Maureen C. Ferran, Gary R. Skuse |
Abstract |
Nonpathogenic fowl adenoviruses (FAdVs) are amenable for engineering multivalent vaccine platforms due to large stretches of nonessential DNA sequences in their genomes. We describe the generation of FAdV-9-based vaccine platforms by targeted homologous recombination in an infectious clone (pPacFAdV-9 or wild type FAdmid) containing the entire viral genome in a cosmid vector. The viral DNA is subsequently released from the cosmid by restriction enzyme digestion followed by transfection in a chicken hepatoma cell line (CH-SAH). Virus is harvested, propagated, and verified for foreign gene expression. |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 27% |
Researcher | 4 | 27% |
Student > Ph. D. Student | 2 | 13% |
Student > Bachelor | 1 | 7% |
Student > Postgraduate | 1 | 7% |
Other | 0 | 0% |
Unknown | 3 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 2 | 13% |
Agricultural and Biological Sciences | 2 | 13% |
Unspecified | 1 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Computer Science | 1 | 7% |
Other | 3 | 20% |
Unknown | 5 | 33% |