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Recombinant Virus Vaccines

Overview of attention for book
Attention for Chapter 14: Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform
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Chapter title
Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform
Chapter number 14
Book title
Recombinant Virus Vaccines
Published in
Methods in molecular biology, April 2017
DOI 10.1007/978-1-4939-6869-5_14
Pubmed ID
Book ISBNs
978-1-4939-6867-1, 978-1-4939-6869-5
Authors

Mattiacio, Jonelle L., Brewer, Matt, Dewhurst, Stephen, Jonelle L. Mattiacio, Matt Brewer, Stephen Dewhurst

Editors

Maureen C. Ferran, Gary R. Skuse

Abstract

The generation of a strong antibody response to target antigens is a major goal for vaccine development. Here we describe the display of the human immunodeficiency virus (HIV) envelope spike protein (Env) on a virus-like scaffold provided by the lambda phage capsid. Phage vectors, in general, have advantages over mammalian virus vectors due to their genetic tractability, inexpensive production, suitability for scale-up, as well as their physical stability, making them an attractive vaccine platform.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 36%
Student > Ph. D. Student 2 18%
Researcher 2 18%
Professor > Associate Professor 1 9%
Unknown 2 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 36%
Biochemistry, Genetics and Molecular Biology 3 27%
Veterinary Science and Veterinary Medicine 1 9%
Immunology and Microbiology 1 9%
Unknown 2 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2017.
All research outputs
#20,412,387
of 22,962,258 outputs
Outputs from Methods in molecular biology
#9,917
of 13,136 outputs
Outputs of similar age
#269,322
of 308,981 outputs
Outputs of similar age from Methods in molecular biology
#231
of 296 outputs
Altmetric has tracked 22,962,258 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,136 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 308,981 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 296 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.