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Translational Anatomy and Cell Biology of Autism Spectrum Disorder

Overview of attention for book
Cover of 'Translational Anatomy and Cell Biology of Autism Spectrum Disorder'

Table of Contents

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    Book Overview
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    Chapter 1 Anatomy and Cell Biology of Autism Spectrum Disorder: Lessons from Human Genetics
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    Chapter 2 Neuroanatomy and Neuropathology of Autism Spectrum Disorder in Humans
  4. Altmetric Badge
    Chapter 3 Modelling Autistic Neurons with Induced Pluripotent Stem Cells
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    Chapter 4 Modelling Autistic Features in Mice Using Quantitative Genetic Approaches
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    Chapter 5 Behavioural Phenotypes and Neural Circuit Dysfunctions in Mouse Models of Autism Spectrum Disorder
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    Chapter 6 Cerebellar and Striatal Pathologies in Mouse Models of Autism Spectrum Disorder
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    Chapter 7 Neurotrophic Factors in Mouse Models of Autism Spectrum Disorder: Focus on BDNF and IGF-1
  9. Altmetric Badge
    Chapter 8 The Role of the Oxytocin/Arginine Vasopressin System in Animal Models of Autism Spectrum Disorder
  10. Altmetric Badge
    Chapter 9 Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder
  11. Altmetric Badge
    Chapter 10 Genetic and Pharmacological Reversibility of Phenotypes in Mouse Models of Autism Spectrum Disorder
Attention for Chapter 3: Modelling Autistic Neurons with Induced Pluripotent Stem Cells
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Chapter title
Modelling Autistic Neurons with Induced Pluripotent Stem Cells
Chapter number 3
Book title
Translational Anatomy and Cell Biology of Autism Spectrum Disorder
Published in
Advances in anatomy embryology and cell biology, May 2017
DOI 10.1007/978-3-319-52498-6_3
Pubmed ID
28551750
Book ISBNs
978-3-31-952496-2, 978-3-31-952498-6
Authors

Annie Kathuria, Carlo Sala, Chiara Verpelli, Jack Price, Kathuria, Annie, Sala, Carlo, Verpelli, Chiara, Price, Jack

Editors

Michael J. Schmeisser, Tobias M. Boeckers

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects more than 1% of children per current estimates. It has been characterised by the following two core behavioural phenotypes: (1) deficits in social interaction and communication and (2) repetitive behaviours, restricted interests and activities. Due to the complex nature of ASD, there are currently no effective treatments. The reason behind this is the clinical and genetic heterogeneity between affected individuals on the one hand and the lack of understanding of the underpinning pathophysiological mechanisms on the other hand. Induced pluripotent stem cells (iPSCs) are reprogrammed stem cells from adult cells. These have the capacity to self-renew and differentiate into any type of cells in the body. Therefore, human iPSCs provide a unique opportunity to study the human cellular and molecular phenotypes associated with ASD. Here, we systematically review various ASD variants and co-morbid diseases modelled using human iPSCs.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 27%
Student > Bachelor 8 22%
Student > Ph. D. Student 4 11%
Student > Doctoral Student 2 5%
Lecturer 2 5%
Other 6 16%
Unknown 5 14%
Readers by discipline Count As %
Neuroscience 8 22%
Nursing and Health Professions 5 14%
Biochemistry, Genetics and Molecular Biology 4 11%
Psychology 4 11%
Social Sciences 2 5%
Other 6 16%
Unknown 8 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2017.
All research outputs
#15,462,982
of 22,977,819 outputs
Outputs from Advances in anatomy embryology and cell biology
#37
of 86 outputs
Outputs of similar age
#197,110
of 313,536 outputs
Outputs of similar age from Advances in anatomy embryology and cell biology
#6
of 10 outputs
Altmetric has tracked 22,977,819 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 86 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,536 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.

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