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Small Molecule Microarrays

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Table of Contents

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    Book Overview
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    Chapter 1 The Expanding World of Small Molecule Microarrays
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    Chapter 2 Novel Substrates for Microarrays
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    Chapter 3 Fabrication of Bio-function-Preserved Saccharide Microarray Chips with Cyanuric Chloride as a Rotatable Linker
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    Chapter 4 Fabrication of Carbohydrate Microarrays by Boronate Formation
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    Chapter 5 Clickable Polymeric Coating for Glycan Microarrays
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    Chapter 6 A Versatile Microarray Immobilization Strategy Based on a Biorthogonal Reaction Between Tetrazine and Trans-Cyclooctene
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    Chapter 7 Label-Free Sensing on Microarrays
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    Chapter 8 Optical Microscopy for Detecting Binding on Small Molecule Microarrays
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    Chapter 9 Array-on-Array Strategy For Activity-Based Enzyme Profiling
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    Chapter 10 Protein–Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays
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    Chapter 11 Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays
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    Chapter 12 Profiling Phosphopeptide-Binding Domain Recognition Specificity Using Peptide Microarrays
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    Chapter 13 Validation Procedure for Multiplex Antibiotic Immunoassays Using Flow-Based Chemiluminescence Microarrays
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    Chapter 14 Large-Scale Interaction Profiling of Protein Domains Through Proteomic Peptide-Phage Display Using Custom Peptidomes
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    Chapter 15 Synthetic Glycan Microarrays
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    Chapter 16 Screening Mammalian Cells on a Hydrogel: Functionalized Small Molecule Microarray
Attention for Chapter 16: Screening Mammalian Cells on a Hydrogel: Functionalized Small Molecule Microarray
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Chapter title
Screening Mammalian Cells on a Hydrogel: Functionalized Small Molecule Microarray
Chapter number 16
Book title
Small Molecule Microarrays
Published in
Methods in molecular biology, November 2016
DOI 10.1007/978-1-4939-6584-7_16
Pubmed ID
Book ISBNs
978-1-4939-6582-3, 978-1-4939-6584-7
Authors

Biwei Zhu, Bo Jiang, Zhenkun Na, Shao Q. Yao

Editors

Mahesh Uttamchandani, Shao Q. Yao

Abstract

Mammalian cell-based microarray technology has gained wide attention, for its plethora of promising applications. The platform is able to provide simultaneous information on multiple parameters for a given target, or even multiple target proteins, in a complex biological system. Here we describe the preparation of mammalian cell-based microarrays using selectively captured of human prostate cancer cells (PC-3). This platform was then used in controlled drug release and measuring the associated drug effects on these cancer cells.

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Mendeley readers

The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 2 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 1 50%
Student > Master 1 50%
Readers by discipline Count As %
Materials Science 1 50%
Medicine and Dentistry 1 50%