Chapter title |
Novel Substrates for Microarrays
|
---|---|
Chapter number | 2 |
Book title |
Small Molecule Microarrays
|
Published in |
Methods in molecular biology, November 2016
|
DOI | 10.1007/978-1-4939-6584-7_2 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6582-3, 978-1-4939-6584-7
|
Authors |
Dameng Guo, Han Wu, Liang Wu, Bo Zheng, Guo, Dameng, Wu, Han, Wu, Liang, Zheng, Bo |
Editors |
Mahesh Uttamchandani, Shao Q. Yao |
Abstract |
In the microarray platform, the surface substrate is critical to the result quality in terms of signal consistency and detection sensitivity. Traditional substrates such as glass and nitrocellulose often entail complicated preparation processes such as the activation and functionalization of the reaction spots and surface blocking to prevent nonspecific molecule adsorption. In addition, coffee-ring morphology of the spots is a common issue in the traditional substrates. To address these issues, we introduced a novel substrate based on fluorinated ethylene propylene (FEP) membrane for microarrays. |
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