Chapter title |
Experimental Models for Neurotrauma Research.
|
---|---|
Chapter number | 16 |
Book title |
Injury Models of the Central Nervous System
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3816-2_16 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3814-8, 978-1-4939-3816-2
|
Authors |
Johan Davidsson, Mårten Risling |
Editors |
Firas H. Kobeissy, C. Edward Dixon, Ronald L. Hayes, Stefania Mondello |
Abstract |
Physical trauma in the central nervous system (CNS) is usually the result of a number of forces in different directions and dimensions. A large number of experimental models have been developed to improve the possibilities to understand the outcome of CNS trauma. In this chapter, we will describe the need for a variety of experimental models for research on traumatic brain injury (TBI) and spinal cord injury (SCI). Models can serve different needs, such as: to test new treatments for injuries, to reveal thresholds for injuries, to provide a better understanding of injury mechanisms, or to test tools and methods for translation between experiments and clinical data. In this chapter, we will discuss on the validation of models and translation between experimental and clinical studies. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 4 | 36% |
Unspecified | 1 | 9% |
Professor | 1 | 9% |
Researcher | 1 | 9% |
Professor > Associate Professor | 1 | 9% |
Other | 1 | 9% |
Unknown | 2 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 2 | 18% |
Biochemistry, Genetics and Molecular Biology | 1 | 9% |
Agricultural and Biological Sciences | 1 | 9% |
Unspecified | 1 | 9% |
Social Sciences | 1 | 9% |
Other | 3 | 27% |
Unknown | 2 | 18% |