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Metabolism in Cancer

Overview of attention for book
Attention for Chapter 1: The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells.
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Chapter title
The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells.
Chapter number 1
Book title
Metabolism in Cancer
Published in
Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer, August 2016
DOI 10.1007/978-3-319-42118-6_1
Pubmed ID
Book ISBNs
978-3-31-942116-2, 978-3-31-942118-6
Authors

Charlene Brault, Almut Schulze, Brault, Charlene, Schulze, Almut

Editors

Thorsten Cramer, Clemens A. Schmitt

Abstract

One of the prerequisites for cell growth and proliferation is the synthesis of macromolecules, including proteins, nucleic acids and lipids. Cells have to alter their metabolism to allow the production of metabolic intermediates that are the precursors for biomass production. It is now evident that oncogenic signalling pathways target metabolic processes on several levels and metabolic reprogramming has emerged as a hallmark of cancer. The increased metabolic demand of cancer cells also produces selective dependencies that could be targeted for therapeutic intervention. Understanding the role of glucose and lipid metabolism in supporting cancer cell growth and survival is crucial to identify essential processes that could provide therapeutic windows for cancer therapy.

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 22%
Student > Master 2 22%
Student > Doctoral Student 1 11%
Other 1 11%
Student > Postgraduate 1 11%
Other 0 0%
Unknown 2 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 33%
Medicine and Dentistry 2 22%
Agricultural and Biological Sciences 1 11%
Unknown 3 33%