Chapter title |
Metabolism in Cancer
|
---|---|
Chapter number | 11 |
Book title |
Metabolism in Cancer
|
Published in |
Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer, August 2016
|
DOI | 10.1007/978-3-319-42118-6_11 |
Pubmed ID | |
Book ISBNs |
978-3-31-942116-2, 978-3-31-942118-6
|
Authors |
Smyl, Christopher, Christopher Smyl |
Editors |
Thorsten Cramer, Clemens A. Schmitt |
Abstract |
Research of the last two decades showed that chronic low-grade inflammation, elevated blood glucose and insulin levels may play role in the onset of a number of non-communicable diseases such as type 2 diabetes and some forms of cancer. Regular exercise and fasting can ameliorate high blood glucose and insulin levels as well as increase the concentration of plasma ketone bodies. These, in consequence, may lead to reduction of inflammation. Exercise or severe restriction of caloric intake is not always advisable for patients, in particular those suffering from cancer. The ketogenic diet (KD), characterized by high fat, moderate protein and very low carbohydrate composition can evoke a physiological state similar to that triggered by exercise or fasting. These attributes of KD prompted its possible use in treatment of a number of metabolic diseases, including several types of malignancies. Although results from clinical studies employing KD in the treatment of cancer are still limited, the results obtained from animal models are encouraging and show that KD presents a viable option as an adjunct therapy for cancer. |
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Scientists | 2 | 9% |
Mendeley readers
Geographical breakdown
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Unknown | 108 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 25 | 23% |
Student > Bachelor | 16 | 15% |
Researcher | 11 | 10% |
Other | 6 | 6% |
Student > Doctoral Student | 6 | 6% |
Other | 21 | 19% |
Unknown | 23 | 21% |
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Medicine and Dentistry | 25 | 23% |
Biochemistry, Genetics and Molecular Biology | 12 | 11% |
Agricultural and Biological Sciences | 5 | 5% |
Sports and Recreations | 4 | 4% |
Other | 13 | 12% |
Unknown | 24 | 22% |