Chapter title |
Characterization of Intracranial Pressure Behavior in Chronic Epileptic Animals: A Preliminary Study.
|
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Chapter number | 65 |
Book title |
Intracranial Pressure and Brain Monitoring XV
|
Published in |
Acta neurochirurgica Supplement, January 2016
|
DOI | 10.1007/978-3-319-22533-3_65 |
Pubmed ID | |
Book ISBNs |
978-3-31-922532-6, 978-3-31-922533-3
|
Authors |
Danilo Augusto Cardim, Gustavo Henrique Frigieri, Brenno Caetano Troca Cabella, Jackeline Moraes Malheiros, Ana Carolina Cardim, Charles Chenwei Wang, Rodrigo de Albuquerque Pacheco Andrade, Luciene Covolan, Alberto Tannús, Sérgio Mascarenhas, Cardim, Danilo Augusto, Frigieri, Gustavo Henrique, Cabella, Brenno Caetano Troca, Malheiros, Jackeline Moraes, Cardim, Ana Carolina, Wang, Charles Chenwei, Albuquerque Pacheco Andrade, Rodrigo de, Covolan, Luciene, Tannús, Alberto, Mascarenhas, Sérgio |
Editors |
Beng-Ti Ang |
Abstract |
Intracranial pressure (ICP) is a major neurological parameter in animals and humans. ICP is a function of the relationship between the contents of the cranium (brain parenchyma, cerebrospinal fluid, and blood) and the volume of the skull. Increased ICP can cause serious physiological effects or even death in patients who do not quickly receive proper care, which includes ICP monitoring. Epilepsies are a set of central nervous system disorders resulting from abnormal and excessive neuronal discharges, usually associated with hypersynchronism and/or hyperexcitability. Temporal lobe epilepsy (TLE) is one of the most common forms of epilepsy and is also refractory to medication. ICP characteristics of subjects with epilepsy have not been elucidated because there are few studies associating these two important neurological factors. In this work, an invasive (ICPi) and the new minimally invasive (ICPmi) methods were used to evaluate ICP features in rats with chronic epilepsy, induced by the experimental model of pilocarpine, capable of generating the main features of human TLE in these animals. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 26% |
Student > Bachelor | 3 | 13% |
Student > Ph. D. Student | 3 | 13% |
Student > Doctoral Student | 2 | 9% |
Student > Master | 2 | 9% |
Other | 5 | 22% |
Unknown | 2 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 35% |
Neuroscience | 6 | 26% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Other | 3 | 13% |
Unknown | 3 | 13% |