Chapter title |
Early Cognitive Domain Deficits in Patients with Aneurysmal Subarachnoid Hemorrhage Correlate with Functional Status.
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Chapter number | 26 |
Book title |
Intracranial Pressure and Brain Monitoring XV
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Published in |
Acta neurochirurgica Supplement, January 2016
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DOI | 10.1007/978-3-319-22533-3_26 |
Pubmed ID | |
Book ISBNs |
978-3-31-922532-6, 978-3-31-922533-3
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Authors |
George Kwok Chu Wong MD, Sandy Wai Lam BSocSc, Adrian Wong PhD, Karine Ngai BSocSc, Vincent Mok MD, Wai Sang Poon FRCS, Wong, George Kwok Chu, Lam, Sandy Wai, Wong, Adrian, Ngai, Karine, Mok, Vincent, Poon, Wai Sang, George Kwok Chu Wong, Sandy Wai Lam, Adrian Wong, Karine Ngai, Vincent Mok, Wai Sang Poon |
Editors |
Beng-Ti Ang |
Abstract |
Cognitive deficits commonly occur after aneurysmal subarachnoid hemorrhage (aSAH), although a few studies systemically evaluate its early impact. We hypothesized that early cognitive domain deficits in patients with aSAH correlate with functional status. We carried out a prospective observational study in Hong Kong, for which patients with aSAH, aged 21-75 years, who had been admitted within 96 h of ictus were recruited. The cognitive assessment used was the domain-specific neuropsychological assessment battery at 2-4 weeks (n = 74) after ictus. Functional status was measured using the modified Rankin Scale (mRS) and the Lawton Instrumental Activity of Daily Living (IADL) scale. The study is registered at ClinicalTrials.gov of the US National Institutes of Health (NCT01038193). Unfavorable outcome (mRS 3-5) was associated with visuospatial memory domain deficit and language domain deficit. Dependent IADL (score <15) was associated with language domain deficit. Visuospatial memory and language are important determinants of early functional status. Whether early targeted rehabilitation can improve functional status should be assessed in a future study. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 64 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 13 | 20% |
Student > Postgraduate | 5 | 8% |
Student > Master | 5 | 8% |
Student > Ph. D. Student | 4 | 6% |
Researcher | 4 | 6% |
Other | 8 | 13% |
Unknown | 25 | 39% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 17 | 27% |
Psychology | 6 | 9% |
Neuroscience | 6 | 9% |
Nursing and Health Professions | 4 | 6% |
Social Sciences | 2 | 3% |
Other | 2 | 3% |
Unknown | 27 | 42% |