Chapter title |
Integrating Proteomics Profiling Data Sets: A Network Perspective
|
---|---|
Chapter number | 14 |
Book title |
Clinical Proteomics
|
Published in |
Methods in molecular biology, October 2014
|
DOI | 10.1007/978-1-4939-1872-0_14 |
Pubmed ID | |
Book ISBNs |
978-1-4939-1871-3, 978-1-4939-1872-0
|
Authors |
Akshay Bhat, Mohammed Dakna, Harald Mischak, Bhat, Akshay, Dakna, Mohammed, Mischak, Harald |
Editors |
Antonia Vlahou, Manousos Makridakis |
Abstract |
Understanding disease mechanisms often requires complex and accurate integration of cellular pathways and molecular networks. Systems biology offers the possibility to provide a comprehensive map of the cell's intricate wiring network, which can ultimately lead to decipher the disease phenotype. Here, we describe what biological pathways are, how they function in normal and abnormal cellular systems, limitations faced by databases for integrating data, and highlight how network models are emerging as a powerful integrative framework to understand and interpret the roles of proteins and peptides in diseases. |
X Demographics
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Canada | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 4 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 13% |
Unknown | 7 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 2 | 25% |
Other | 1 | 13% |
Student > Master | 1 | 13% |
Professor | 1 | 13% |
Professor > Associate Professor | 1 | 13% |
Other | 1 | 13% |
Unknown | 1 | 13% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 3 | 38% |
Computer Science | 2 | 25% |
Biochemistry, Genetics and Molecular Biology | 2 | 25% |
Unknown | 1 | 13% |