Report for: Molecular Mechanisms of Cell Differentiation in Gonad Development

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Chapter title	Molecular Mechanisms of Cell Differentiation in Gonad Development
Chapter number	10
Book title	Molecular Mechanisms of Cell Differentiation in Gonad Development
Published in	Results and problems in cell differentiation, June 2016
DOI	10.1007/978-3-319-31973-5_10
Pubmed ID	27300182
Book ISBNs	978-3-31-931971-1, 978-3-31-931973-5
Authors	Mecklenburg, Jennifer M, Hermann, Brian P, Jennifer M. Mecklenburg, Brian P. Hermann Ph.D., Brian P. Hermann
Editors	Rafal P. Piprek
Abstract	Mammalian spermatogenesis is a complex and highly ordered process by which male germ cells proceed through a series of differentiation steps to produce haploid flagellated spermatozoa. Underlying this process is a pool of adult stem cells, the spermatogonial stem cells (SSCs), which commence the spermatogenic lineage by undertaking a differentiation fate decision to become progenitor spermatogonia. Subsequently, progenitors acquire a differentiating spermatogonia phenotype and undergo a series of amplifying mitoses while becoming competent to enter meiosis. After spermatocytes complete meiosis, post-meiotic spermatids must then undergo a remarkable transformation from small round spermatids to a flagellated spermatozoa with extremely compacted nuclei. This chapter reviews the current literature pertaining to spermatogonial differentiation with an emphasis on the mechanisms controlling stem cell fate decisions and early differentiation events in the life of a spermatogonium.

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Geographical breakdown

Country	Count	As %
Japan	1	100%

Demographic breakdown

Type	Count	As %
Members of the public	1	100%

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Unknown	27	100%

Demographic breakdown

Readers by professional status	Count	As %
Student > Ph. D. Student	6	22%
Student > Master	4	15%
Student > Doctoral Student	3	11%
Student > Bachelor	2	7%
Professor > Associate Professor	2	7%
Other	1	4%
Unknown	9	33%

Readers by discipline	Count	As %
Biochemistry, Genetics and Molecular Biology	7	26%
Agricultural and Biological Sciences	5	19%
Medicine and Dentistry	4	15%
Unknown	11	41%

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#20,333,181

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Outputs from Results and problems in cell differentiation

#163

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#304,691

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Molecular Mechanisms of Cell Differentiation in Gonad Development

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