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HCV: The Journey from Discovery to a Cure

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Cover of 'HCV: The Journey from Discovery to a Cure'

Table of Contents

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    Book Overview
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    Chapter 43 The Clinical Development of Sofosbuvir/Velpatasvir (SOF/VEL, Epclusa ® )
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    Chapter 44 Discovery of Elbasvir
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    Chapter 45 NS5A as a Target for HCV Drug Discovery
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    Chapter 46 Evolution of HCV NS4B Inhibitors
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    Chapter 47 The Discovery and Development of Daclatasvir: An Inhibitor of the Hepatitis C Virus NS5A Replication Complex
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    Chapter 48 The Clinical Development of Ledipasvir/Sofosbuvir (LDV/SOF, Harvoni ® )
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    Chapter 49 The Clinical Development of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX, Vosevi ® )
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    Chapter 50 HCV NS5A as an Antiviral Therapeutic Target: From Validation to the Discovery and Development of Ombitasvir and Pibrentasvir as Components of IFN-Sparing HCV Curative Treatments
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    Chapter 52 The Benefit of Direct-Acting Antiviral HCV Cure Therapies
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    Chapter 54 Development of ZEPATIER ®
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    Chapter 56 Cure and Control: What Will It Take to Eliminate HCV?
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    Chapter 60 Clinical Development of Viekira Pak to Mavyret
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    Chapter 63 Real-World Evidence and Hepatitis C
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    Chapter 64 The Evolution of Clinical Trials for Hepatitis C
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    Chapter 65 Perspectives on HCV Cure
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    Chapter 66 The Discovery of Ledipasvir (GS-5885): The Potent Once-Daily Oral HCV NS5A Inhibitor in the Single-Tablet Regimen Harvoni ®
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    Chapter 67 The Discovery of Velpatasvir (GS-5816): The Potent Pan-Genotypic Once-Daily Oral HCV NS5A Inhibitor in the Single-Tablet Regimens Epclusa and Vosevi ®
Attention for Chapter 50: HCV NS5A as an Antiviral Therapeutic Target: From Validation to the Discovery and Development of Ombitasvir and Pibrentasvir as Components of IFN-Sparing HCV Curative Treatments
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Chapter title
HCV NS5A as an Antiviral Therapeutic Target: From Validation to the Discovery and Development of Ombitasvir and Pibrentasvir as Components of IFN-Sparing HCV Curative Treatments
Chapter number 50
Book title
HCV: The Journey from Discovery to a Cure
Published by
Springer, Cham, January 2019
DOI 10.1007/7355_2018_50
Book ISBNs
978-3-03-028399-5, 978-3-03-028400-8
Authors

Rolf Wagner, David A. DeGoey, John T. Randolph, Allan C. Krueger, Mark A. Matulenko, Warren M. Kati

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 1 25%
Student > Postgraduate 1 25%
Student > Master 1 25%
Unknown 1 25%
Readers by discipline Count As %
Chemistry 2 50%
Medicine and Dentistry 1 25%
Unknown 1 25%