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HCV: The Journey from Discovery to a Cure

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Cover of 'HCV: The Journey from Discovery to a Cure'

Table of Contents

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    Book Overview
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    Chapter 43 The Clinical Development of Sofosbuvir/Velpatasvir (SOF/VEL, Epclusa ® )
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    Chapter 44 Discovery of Elbasvir
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    Chapter 45 NS5A as a Target for HCV Drug Discovery
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    Chapter 46 Evolution of HCV NS4B Inhibitors
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    Chapter 47 The Discovery and Development of Daclatasvir: An Inhibitor of the Hepatitis C Virus NS5A Replication Complex
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    Chapter 48 The Clinical Development of Ledipasvir/Sofosbuvir (LDV/SOF, Harvoni ® )
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    Chapter 49 The Clinical Development of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX, Vosevi ® )
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    Chapter 50 HCV NS5A as an Antiviral Therapeutic Target: From Validation to the Discovery and Development of Ombitasvir and Pibrentasvir as Components of IFN-Sparing HCV Curative Treatments
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    Chapter 52 The Benefit of Direct-Acting Antiviral HCV Cure Therapies
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    Chapter 54 Development of ZEPATIER ®
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    Chapter 56 Cure and Control: What Will It Take to Eliminate HCV?
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    Chapter 60 Clinical Development of Viekira Pak to Mavyret
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    Chapter 63 Real-World Evidence and Hepatitis C
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    Chapter 64 The Evolution of Clinical Trials for Hepatitis C
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    Chapter 65 Perspectives on HCV Cure
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    Chapter 66 The Discovery of Ledipasvir (GS-5885): The Potent Once-Daily Oral HCV NS5A Inhibitor in the Single-Tablet Regimen Harvoni ®
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    Chapter 67 The Discovery of Velpatasvir (GS-5816): The Potent Pan-Genotypic Once-Daily Oral HCV NS5A Inhibitor in the Single-Tablet Regimens Epclusa and Vosevi ®
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Title
HCV: The Journey from Discovery to a Cure
Published by
Springer International Publishing, March 2020
DOI 10.1007/978-3-030-28400-8
ISBNs
978-3-03-028399-5, 978-3-03-028400-8
Editors

Sofia, Michael J.

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