| Chapter title |
Diagnosis and Management of Hereditary Renal Cell Cancer.
|
|---|---|
| Chapter number | 6 |
| Book title |
Rare Hereditary Cancers
|
| Published in |
Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer, April 2016
|
| DOI | 10.1007/978-3-319-29998-3_6 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-929996-9, 978-3-31-929998-3
|
| Authors |
Fred H. Menko, Eamonn R. Maher, Menko, Fred H, Maher, Eamonn R, Menko, Fred H., Maher, Eamonn R. |
| Editors |
Gabriella Pichert, Chris Jacobs |
| Abstract |
Renal cell cancer (RCC) is the common denominator for a heterogeneous group of diseases. The subclassification of these tumours is based on histological type and molecular pathogenesis. Insight into molecular pathogenesis has led to the development of targeted systemic therapies. Genetic susceptibility is the principal cause of RCC in about 2-4 % of cases. Hereditary RCC is the umbrella term for about a dozen different conditions, the most frequent of which is von Hippel-Lindau disease . Here, we describe the main hereditary RCC syndromes, consider criteria for referral of RCC patients for clinical genetic assessment and discuss management options for patients with hereditary RCC and their at-risk relatives. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 14 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 2 | 14% |
| Student > Doctoral Student | 1 | 7% |
| Professor | 1 | 7% |
| Student > Ph. D. Student | 1 | 7% |
| Student > Master | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 7 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 3 | 21% |
| Medicine and Dentistry | 2 | 14% |
| Neuroscience | 1 | 7% |
| Earth and Planetary Sciences | 1 | 7% |
| Unknown | 7 | 50% |