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Cannabinoids

Overview of attention for book
Cover of 'Cannabinoids'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Pharmacological actions of cannabinoids.
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    Chapter 2 Cannabinoid Receptor Signaling
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    Chapter 3 Molecular Biology of Cannabinoid Receptors
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    Chapter 4 Analysis of the Endocannabinoid System by Using CB1 Cannabinoid Receptor Knockout Mice
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    Chapter 5 The Biosynthesis, Fate and Pharmacological Properties of Endocannabinoids
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    Chapter 6 Modulators of Endocannabinoid Enzymic Hydrolysis and Membrane Transport
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    Chapter 7 Structural Requirements for Cannabinoid Receptor Probes
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    Chapter 8 Cannabinoid Receptors and Their Ligands: Ligand—Ligand and Ligand—Receptor Modeling Approaches
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    Chapter 9 The phylogenetic distribution and evolutionary origins of endocannabinoid signalling
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    Chapter 10 Distribution of Cannabinoid Receptors in the Central and Peripheral Nervous System
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    Chapter 11 Effects of Cannabinoids on Neurotransmission
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    Chapter 12 Retrograde Signalling by Endocannabinoids
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    Chapter 13 Effects on the immune system.
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    Chapter 14 Imaging of the Brain Cannabinoid System
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    Chapter 15 Cannabinoid function in learning, memory and plasticity.
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    Chapter 16 Cannabinoid Control of Motor Function at the Basal Ganglia
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    Chapter 17 Cannabinoid Mechanisms of Pain Suppression
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    Chapter 18 Effects of cannabinoids on hypothalamic and reproductive function.
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    Chapter 19 Cannabinoids and the digestive tract.
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    Chapter 20 Cardiovascular Pharmacology of Cannabinoids
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    Chapter 21 Effects on cell viability.
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    Chapter 22 Effects on Development
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    Chapter 24 Cannabinoid Tolerance and Dependence
  25. Altmetric Badge
    Chapter 25 Human Studies of Cannabinoids and Medicinal Cannabis
Attention for Chapter 19: Cannabinoids and the digestive tract.
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#31 of 684)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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2 news outlets
twitter
7 X users
facebook
6 Facebook pages
wikipedia
5 Wikipedia pages
googleplus
10 Google+ users

Citations

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106 Dimensions

Readers on

mendeley
65 Mendeley
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Chapter title
Cannabinoids and the digestive tract.
Chapter number 19
Book title
Cannabinoids
Published in
Handbook of experimental pharmacology, April 2006
DOI 10.1007/3-540-26573-2_19
Pubmed ID
Book ISBNs
978-3-54-022565-2, 978-3-54-026573-3
Authors

Izzo AA, Coutts AA, A. A. Izzo, A. A. Coutts, Izzo, A. A., Coutts, A. A.

Abstract

In the digestive tract there is evidence for the presence of high levels of endocannabinoids (anandamide and 2-arachidonoylglycerol) and enzymes involved in the synthesis and metabolism of endocannabinoids. Immunohistochemical studies have shown the presence of CB1 receptors on myenteric and submucosal nerve plexuses along the alimentary tract. Pharmacological studies have shown that activation of CB1 receptors produces relaxation of the lower oesophageal sphincter, inhibition of gastric motility and acid secretion, as well as intestinal motility and secretion. In general, CB1-induced inhibition of intestinal motility and secretion is due to reduced acetylcholine release from enteric nerves. Conversely, endocannabinoids stimulate intestinal primary sensory neurons via the vanilloid VR1 receptor, resulting in enteritis and enhanced motility. The endogenous cannabinoid system has been found to be involved in the physiological control of colonic motility and in some pathophysiological states, including paralytic ileus, intestinal inflammation and cholera toxin-induced diarrhoea. Cannabinoids also possess antiemetic effects mediated by activation of central and peripheral CB1 receptors. Pharmacological modulation of the endogenous cannabinoid system could provide a new therapeutic target for the treatment of a number of gastrointestinal diseases, including nausea and vomiting, gastric ulcers, secretory diarrhoea, paralytic ileus, inflammatory bowel disease, colon cancer and gastro-oesophageal reflux conditions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 2%
Belgium 1 2%
Unknown 63 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 25%
Student > Bachelor 9 14%
Student > Ph. D. Student 8 12%
Student > Master 7 11%
Student > Doctoral Student 4 6%
Other 14 22%
Unknown 7 11%
Readers by discipline Count As %
Medicine and Dentistry 18 28%
Agricultural and Biological Sciences 14 22%
Pharmacology, Toxicology and Pharmaceutical Science 6 9%
Biochemistry, Genetics and Molecular Biology 5 8%
Chemistry 4 6%
Other 9 14%
Unknown 9 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2023.
All research outputs
#1,018,948
of 25,176,926 outputs
Outputs from Handbook of experimental pharmacology
#31
of 684 outputs
Outputs of similar age
#1,491
of 78,291 outputs
Outputs of similar age from Handbook of experimental pharmacology
#3
of 13 outputs
Altmetric has tracked 25,176,926 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 684 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 78,291 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.