Chapter title |
Target Therapy in Lung Cancer.
|
---|---|
Chapter number | 6 |
Book title |
Lung Cancer and Personalized Medicine
|
Published in |
Advances in experimental medicine and biology, December 2015
|
DOI | 10.1007/978-3-319-24223-1_6 |
Pubmed ID | |
Book ISBNs |
978-3-31-924221-7, 978-3-31-924223-1
|
Authors |
Stefano Cafarotti, Filippo Lococo, Patrizia Froesh, Francesco Zappa, Dutly Andrè |
Editors |
Aamir Ahmad, Shirish Gadgeel |
Abstract |
Lung cancer is an extremely heterogeneous disease, with well over 50 different histological variants recognized under the fourth revision of the World Health Organization (WHO) typing system [1]. Because these variants have differing genetic and biological properties correct classification of lung cancer is necessary to assure that lung cancer patients receive optimum management. Due to the recent understanding that histologic typing and EGFR mutation status are important for target the therapy in lung adenocarcinoma patients [2] there was a great need for a new classification that addresses diagnostic issues and strategic management to allow for molecular testing in small biopsy and cytology specimens. For this reason and in order to address advances in lung cancer treatment an international multidisciplinary classification was proposed by the International Association for the Study of Lung Cancer (IASLC), American Thoracic Society (ATS), and European Respiratory Society (ERS) [3], further increasing the histological heterogeneity and improving the existing WHO-classification. Is now the beginning of personalized therapy era that is ideally finalized to treat each individual case of lung cancer in different way. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 3 | 15% |
Student > Ph. D. Student | 3 | 15% |
Researcher | 3 | 15% |
Student > Master | 3 | 15% |
Student > Doctoral Student | 1 | 5% |
Other | 2 | 10% |
Unknown | 5 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 7 | 35% |
Medicine and Dentistry | 4 | 20% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 10% |
Agricultural and Biological Sciences | 1 | 5% |
Chemistry | 1 | 5% |
Other | 0 | 0% |
Unknown | 5 | 25% |