| Chapter title |
Lung Cancer in Never Smokers.
|
|---|---|
| Chapter number | 3 |
| Book title |
Lung Cancer and Personalized Medicine
|
| Published in |
Advances in experimental medicine and biology, December 2015
|
| DOI | 10.1007/978-3-319-24223-1_3 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-924221-7, 978-3-31-924223-1
|
| Authors |
Gabriel Alberto Rivera, Heather Wakelee, Rivera, Gabriel Alberto, Wakelee, Heather |
| Editors |
Aamir Ahmad, Shirish Gadgeel |
| Abstract |
Lung cancer is predominantly associated with cigarette smoking; however, a substantial minority of patients with the disease have never smoked. In the US it is estimated there are 17,000-26,000 annual deaths from lung cancer in never smokers, which as a separate entity would be the seventh leading cause of cancer mortality. Controversy surrounds the question of whether or not the incidence of lung cancer in never-smokers is increasing, with more data to support this observation in Asia. There are several factors associated with an increased risk of developing lung cancer in never smokers including second hand smoke, indoor air pollution, occupational exposures, and genetic susceptibility among others. Adenocarcinoma is the most common histology of lung cancer in never smokers and in comparison to lung cancer in smokers appears less complex with a higher likelihood to have targetable driver mutations. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 233 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 37 | 16% |
| Student > Master | 24 | 10% |
| Student > Ph. D. Student | 16 | 7% |
| Student > Postgraduate | 14 | 6% |
| Researcher | 11 | 5% |
| Other | 32 | 14% |
| Unknown | 99 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 61 | 26% |
| Biochemistry, Genetics and Molecular Biology | 27 | 12% |
| Nursing and Health Professions | 11 | 5% |
| Agricultural and Biological Sciences | 4 | 2% |
| Engineering | 4 | 2% |
| Other | 22 | 9% |
| Unknown | 104 | 45% |