Chapter title |
Lipids in Plant and Algae Development
|
---|---|
Chapter number | 19 |
Book title |
Lipids in Plant and Algae Development
|
Published in |
Sub cellular biochemistry, March 2016
|
DOI | 10.1007/978-3-319-25979-6_19 |
Pubmed ID | |
Book ISBNs |
978-3-31-925977-2, 978-3-31-925979-6
|
Authors |
Khozin-Goldberg, Inna, Leu, Stefan, Boussiba, Sammy, Inna Khozin-Goldberg, Stefan Leu, Sammy Boussiba |
Editors |
Yuki Nakamura, Yonghua Li-Beisson |
Abstract |
Microalgae present a huge and still insufficiently tapped resource of very long-chain omega-3 and omega-6 polyunsaturated fatty acids (VLC-PUFA) for human nutrition and medicinal applications. This chapter describes the diversity of unicellular eukaryotic microalgae in respect to VLC-PUFA biosynthesis. Then, we outline the major biosynthetic pathways mediating the formation of VLC-PUFA by sequential desaturation and elongation of C18-PUFA acyl groups. We address the aspects of spatial localization of those pathways and elaborate on the role for VLC-PUFA in microalgal cells. Recent progress in microalgal genetic transformation and molecular engineering has opened the way to increased production efficiencies for VLC-PUFA. The perspectives of photobiotechnology and metabolic engineering of microalgae for altered or enhanced VLC-PUFA production are also discussed. |
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