Chapter title |
microRNAs and Endometrial Pathophysiology
|
---|---|
Chapter number | 8 |
Book title |
microRNA: Basic Science
|
Published in |
Advances in experimental medicine and biology, January 2015
|
DOI | 10.1007/978-3-319-22380-3_8 |
Pubmed ID | |
Book ISBNs |
978-3-31-922379-7, 978-3-31-922380-3
|
Authors |
Henry H. Chill, Uri P. Dior, Liron Kogan, Ariel Revel |
Abstract |
Embryo implantation requires a reciprocal interaction between the blastocyst and endometrium and is associated with complex regulatory mechanisms. Since their discovery, microRNAs became prominent candidates providing missing links for many biological pathways. In recent years, microRNAs were implicated as one of the important players in regulation of various biological and physiological endometrial related processes. This chapter aims to present recent knowledge pertaining to the diverse aspects of microRNAs in the embryo-endometrial relationship. We will focus on the role of microRNAs in decidualization and their part in natural and stimulated cycles. Next, we will present recent studies deliberating the role of microRNAs in recurrent pregnancy loss and in the important phenomenon of recurrent implantation failure. Lastly, demonstrating an important aspect of embryo implantation and invasion, we will outline few microRNA related shared pathways of implantation and carcinogenesis. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 3 | 18% |
Student > Ph. D. Student | 3 | 18% |
Researcher | 2 | 12% |
Student > Doctoral Student | 1 | 6% |
Student > Bachelor | 1 | 6% |
Other | 4 | 24% |
Unknown | 3 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 24% |
Medicine and Dentistry | 4 | 24% |
Social Sciences | 2 | 12% |
Agricultural and Biological Sciences | 1 | 6% |
Psychology | 1 | 6% |
Other | 0 | 0% |
Unknown | 5 | 29% |