Chapter title |
Introduction to Techniques and Methodologies for Characterizing the Human Respiratory Virome
|
---|---|
Chapter number | 9 |
Book title |
The Human Virome
|
Published in |
Methods in molecular biology, August 2018
|
DOI | 10.1007/978-1-4939-8682-8_9 |
Pubmed ID | |
Book ISBNs |
978-1-4939-8681-1, 978-1-4939-8682-8
|
Authors |
Alicia B. Mitchell, Allan R. Glanville, Mitchell, Alicia B., Glanville, Allan R. |
Abstract |
There have been great advances in the methodologies available for the detection of respiratory viruses. Accompanying this, our knowledge surrounding the impact of these viruses has also made a great leap forward. We have come a long way from the once commonly accepted belief that the lower respiratory tract was sterile and that the detection of any microbial species must represent a breach in host defence and likely be associated with symptomatic infection. With the advent of molecular detection techniques and improvements in sequencing-based methodologies to make these tools more accessible and cost effective, we now know that there is an abundant and diverse ecosystem within the lower-respiratory tract. This chapter will outline the clinical impact of the human respiratory virome, techniques for sampling the lower respiratory tract, the evolution of the diagnostic tools available, and the current limitations in our instruments and knowledge in this area. The human respiratory virome is an exciting new area of research that will continue to grow with the aid of the methodologies outlined in the following chapters and the advent of even more efficient tools in the future. |
X Demographics
Geographical breakdown
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 6 | 19% |
Researcher | 5 | 16% |
Student > Bachelor | 4 | 13% |
Other | 2 | 6% |
Student > Ph. D. Student | 2 | 6% |
Other | 4 | 13% |
Unknown | 8 | 26% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 10 | 32% |
Medicine and Dentistry | 4 | 13% |
Immunology and Microbiology | 2 | 6% |
Agricultural and Biological Sciences | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 2 | 6% |
Unknown | 11 | 35% |